Ignite Creation Date:
2024-05-05 @ 11:59 AM
Last Modification Date:
2024-10-26 @ 9:18 AM
Study NCT ID:
NCT00207779
Status:
COMPLETED
Last Update Posted:
2007-09-20
First Post:
2005-09-13
Brief Title:
Prevention of Catheter-Related Bloodstream Infection in Patients With Haemato-Oncological Disease
Sponsor:
Centre National de Greffe de Moelle Osseuse
Organization:
Centre National de Greffe de Moelle Osseuse
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2007-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
We the researchers at Centre National de Greffe de Moelle Osseuse have shown in a randomised study in press that a low dose of unfractionated heparin 100 IUkgdaily was safe and effective to prevent catheter-related bloodstream infection in patients with haemato-oncological disease
The aim of this prospective randomised controlled trial is to compare the incidence of catheter-related bloodstream infection in 2 groups of patients with haemato-oncological disease
Group A heparin impregnated catheters
Group B low-dose unfractionated heparin 100 IUkgdaily
The aim of this prospective randomised controlled trial is to compare the incidence of catheter-related bloodstream infection in 2 groups of patients with haemato-oncological disease
Group A heparin impregnated catheters
Group B low-dose unfractionated heparin 100 IUkgdaily
Detailed Description:
Studies have shown that catheter-related infection may be due to fibrin deposition associated with catheters Interventions designed to decrease fibrin deposition and thrombus formation have the potential to reduce catheter-related infections Seven randomised studies have been performed to assess the safety and efficacy of heparin either as an infusion or bonded to central venous catheter on central venous catheter-related bloodstream infections Although a meta-analysis of 4 studies looking at heparin either as an infusion or bonded to central venous catheter showed a strong trend for a reduction in catheter-related bloodstream infection with the use of heparin these studies used variable definitions of catheter-related infections
We have shown in a randomised study in press that low dose of unfractionated heparin 100 IUkgdaily was safe and effective to prevent catheter-related bloodstream infection in patients with haemato-oncological disease The aim of this prospective randomised controlled trial is to compare the incidence of catheter-related bloodstream infection in 2 groups of patients with haemato-oncological disease
Group A heparin impregnated catheters
Group B low-dose unfractionated heparin 100 IUkgdaily
We have shown in a randomised study in press that low dose of unfractionated heparin 100 IUkgdaily was safe and effective to prevent catheter-related bloodstream infection in patients with haemato-oncological disease The aim of this prospective randomised controlled trial is to compare the incidence of catheter-related bloodstream infection in 2 groups of patients with haemato-oncological disease
Group A heparin impregnated catheters
Group B low-dose unfractionated heparin 100 IUkgdaily
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None