Viewing Study NCT02501603



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Last Modification Date: 2024-10-26 @ 11:46 AM
Study NCT ID: NCT02501603
Status: COMPLETED
Last Update Posted: 2023-01-27
First Post: 2015-07-08

Brief Title: Afatinib Paclitaxel 2nd Line Advanced Gastric Cancer
Sponsor: Yonsei University
Organization: Yonsei University

Study Overview

Official Title: An Open-label Multicenter Phase II Study of Afatinib Plus Weekly Taxol as Second Line Treatment for AdvancedRecurrent Gastric and Gastroesophageal Junction Cancer
Status: COMPLETED
Status Verified Date: 2023-01
Last Known Status: None
Delayed Posting: No
If Stopped, Why?: Not Stopped
Has Expanded Access: False
If Expanded Access, NCT#: N/A
Has Expanded Access, NCT# Status: N/A
Acronym: None
Brief Summary: For the gastric cancer paclitaxel is recommended as salvage standard treatment Afatinib is a novel potent small ErbB family blocker that covalently binds and irreversibly blocks signaling through activated EGFR HER2 and ErbB4 receptors as well as the transphosphorylation of ErbB3 The investigators suggest a randomized phase II trial of afatinib plus weekly taxolpaclitaxel for previously treated EGFR positive gastric cancer patients The aim of current trial is to evaluate the antitumor efficacy of afatinib for target enriched patients in gastric cancer
Detailed Description: None

Study Oversight

Has Oversight DMC: None
Is a FDA Regulated Drug?: None
Is a FDA Regulated Device?: None
Is an Unapproved Device?: None
Is a PPSD?: None
Is a US Export?: None
Is an FDA AA801 Violation?: None