Ignite Creation Date:
2024-05-06 @ 7:15 AM
Last Modification Date:
2024-10-26 @ 11:46 AM
Study NCT ID:
NCT02500069
Status:
COMPLETED
Last Update Posted:
2015-07-16
First Post:
2014-03-18
Brief Title:
Location Specific Differences in Intestinal Brake Activation
Sponsor:
Maastricht University Medical Center
Organization:
Maastricht University Medical Center
Study Overview
Official Title:
The Effect of Intestinal Brake Activation at Different Locations in the Gut on Food Intake and Hormone Release
Status:
COMPLETED
Status Verified Date:
2015-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The appearance of intact macronutrients in the small intestine can result in the activation of an intestinal brake a negative feedback mechanism from different parts of the intestine to the stomach the small intestine and to the central nervous system These processes inhibit food processing appetite sensations and food intake and furthermore they increase feelings of satiety and satiation The researchers will investigate the effects of intraduodenal intrajejunal and intralileal infusion of casein protein on ad libitum food intake satiation and in vivo release of the gut satiety peptides CCK PYY and GLP-1 and glucose and insulin
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None