Ignite Creation Date:
2024-05-06 @ 7:14 AM
Last Modification Date:
2024-10-26 @ 11:46 AM
Study NCT ID:
NCT02499445
Status:
COMPLETED
Last Update Posted:
2015-07-16
First Post:
2015-03-05
Brief Title:
Myocardial Injury in Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimens in OPCAB Surgery
Sponsor:
Konkuk University Medical Center
Organization:
Konkuk University Medical Center
Study Overview
Official Title:
Comparisons of Myocardial Injury After Using Different Anesthetics Regimens for Off-pump Coronary Artery Bypass Surgery Remifentanil-based Versus Sevoflurane-sufentanil Balanced Regimen
Status:
COMPLETED
Status Verified Date:
2015-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In patients undergoing off-pump coronary artery bypass OPCAB surgery with different anesthesia regimens remifentanil 075 mcgkgmin and propofol TCI effect-site concentration 08-15 mcgml Group -RP remifentanil 075 mcgkgmin and sevoflurane end-tidal 08 vol Group-RS or sevoflurane end-tidal 12-28 vol-sufentanil TCI effect site concentration 035-075 ngml Group-SS intergroup difference in the level of Troponin I c-TnI and creatinine kinase subtype-MB is determined before surgery control during vascular graft harvesting harvesting after completing graft construction postgrafting and one day after surgery postoperative
Detailed Description:
To determine the difference of myocardial injury upon using different anesthesia regimens remifentanil-based regimen versus sevoflurane-sufentanil balanced regimen
Patients undergoing off-pump coronary artery bypass OPCAB surgery are randomly allocated to get remifentanil 075 mcgkgmin and propofol TCI effect-site concentration 08-15 mcgml Group -RP remifentanil 075 mcgkgmin and sevoflurane end-tidal 08 vol Group-RS or sevoflurane end-tidal 12-28 vol-sufentanil TCI effect site concentration035-075 ngml Group-SS
Intergroup difference in the level of Troponin I c-TnI and creatine kinase-MB is determined before surgery control during vascular graft harvesting harvesting after completing graft construction postgrafting 1 day after surgery postoperative
Patients undergoing off-pump coronary artery bypass OPCAB surgery are randomly allocated to get remifentanil 075 mcgkgmin and propofol TCI effect-site concentration 08-15 mcgml Group -RP remifentanil 075 mcgkgmin and sevoflurane end-tidal 08 vol Group-RS or sevoflurane end-tidal 12-28 vol-sufentanil TCI effect site concentration035-075 ngml Group-SS
Intergroup difference in the level of Troponin I c-TnI and creatine kinase-MB is determined before surgery control during vascular graft harvesting harvesting after completing graft construction postgrafting 1 day after surgery postoperative
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None