Ignite Creation Date:
2024-05-06 @ 7:13 AM
Last Modification Date:
2024-10-26 @ 11:46 AM
Study NCT ID:
NCT02498938
Status:
COMPLETED
Last Update Posted:
2016-08-29
First Post:
2015-07-13
Brief Title:
The Association of SERPINA1 Gene Disturbance in Patients With Lung and Gum Disorders
Sponsor:
Panineeya Mahavidyalaya Institute of Dental Sciences Research Centre
Organization:
Panineeya Mahavidyalaya Institute of Dental Sciences Research Centre
Study Overview
Official Title:
Evaluation of SERPINA1 Gene Polymorphisms in COPD as a Risk Factor for Periodontitis
Status:
COMPLETED
Status Verified Date:
2016-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
SA1PLG
Brief Summary:
Chronic obstructive pulmonary disease and periodontitis are chronic inflammatory diseases The study aims to determine if the genetic polymorphism of SERPINA1 gene in patients with COPD serve as a risk factor for developing periodontitis
Detailed Description:
periodontitis is a polymicrobial inflammatory disease caused by various modifiable and non-modifiable risk factors the non-modifiable risk factors include genetic polymorphisms like the gene coding for alpha-1-antitrypsinase
COPD is a chronic inflammatory disease characterized by deterioration of lung function due to loss of elasticity of the lungs
SERPINA1 gene product has a protective role on the connective tissue components of both lungs and gums
Hence this study tries to determine if the gene polymorphism in COPD serves as a risk factor for developing periodontitis
COPD is a chronic inflammatory disease characterized by deterioration of lung function due to loss of elasticity of the lungs
SERPINA1 gene product has a protective role on the connective tissue components of both lungs and gums
Hence this study tries to determine if the gene polymorphism in COPD serves as a risk factor for developing periodontitis
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None