Ignite Creation Date:
2025-12-24 @ 3:33 PM
Ignite Modification Date:
2025-12-30 @ 6:38 AM
Study NCT ID:
NCT06299592
Status:
RECRUITING
Last Update Posted:
2025-09-03
First Post:
2024-02-29
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Comparison of Microglial Activation in Severe Asthma and Healthy Controls
Sponsor:
University of Wisconsin, Madison
Organization:
Study Overview
Official Title:
Comparison of Microglial Activation in Severe Asthma and Healthy Controls
Status:
RECRUITING
Status Verified Date:
2025-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
MAIA-SC
Brief Summary:
The goal of this clinical trial is to learn about how asthma influences brain function. The main questions it aims to answer are:
* How airway inflammation in asthma affects the brain; and,
* Whether airway inflammation in asthma is related to symptoms of depression and anxiety
Over the course of 3 visits, participants will:
* Complete questionnaires
* Complete computer tasks
* Undergo allergy skin test and breathing tests
* Give two blood samples
* Give a sputum sample
* Complete brain imaging scans
Researchers will compare results between participants with asthma, and participants who do not have asthma.
* How airway inflammation in asthma affects the brain; and,
* Whether airway inflammation in asthma is related to symptoms of depression and anxiety
Over the course of 3 visits, participants will:
* Complete questionnaires
* Complete computer tasks
* Undergo allergy skin test and breathing tests
* Give two blood samples
* Give a sputum sample
* Complete brain imaging scans
Researchers will compare results between participants with asthma, and participants who do not have asthma.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
True
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 1RF1AG082215-01 | NIH | None | https://reporter.nih.gov/quic… | View |
| A538900 | OTHER | UW Madison | View | |
| SMPH/PSYCHIATRY/PSYCHIATRY | OTHER | UW Madison | View | |
| Protocol Version 7/1/2025 | OTHER | UW Madison | View |