Ignite Creation Date:
2024-05-06 @ 7:12 AM
Last Modification Date:
2024-10-26 @ 11:46 AM
Study NCT ID:
NCT02489747
Status:
COMPLETED
Last Update Posted:
2016-03-15
First Post:
2015-06-30
Brief Title:
Effects of Wheat Bran Extract on Cognitive and Memory Function
Sponsor:
Chonbuk National University Hospital
Organization:
Chonbuk National University Hospital
Study Overview
Official Title:
Efficacy and Safety of Wheat Bran Extract on Improvement of Cognitive and Memory Function
Status:
COMPLETED
Status Verified Date:
2016-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The investigators performed a 12-week randomized double-blind placebo-controlled human trial to evaluate the efficacy and safety of water extract from wheat Triticum aestivum L on cognitive and memory function The investigators measured changes in cognitive function parameters including CNT WMT K-MMSE BCRS PRMQ PSS SF-36 and BDNF
Detailed Description:
Based on reports about the neuroprotective effects of water extract from wheat Triticum aestivum L or its bran the investigators hypothesize that extract of wheat bran WBE is beneficial to elderly people with age-associated cognitive impairment The investigators investigated the efficacy and safety of WBE on improvement of cognitive function through measuring the neuropsychometric assessments in adult with subjective cognitive impairment by a randomized clinical trial
Seventy participants aged from 50 to 80 years old with subjective cognitive impairment were randomly assigned to receive either WBE 3000 mgday in this 12-week double-blind placebo-controlled and parallel trial Neuropsychological assessments including Computerized Neurocognitive function test CNT Working Memory Test WMT Korean Mini-Mental State Examination K-MMSE Brief Cognitive Rating Scale BCRS Prospective and Retrospective Memory Questionnaire PRMQ Perceived Stress Scale PSS 36-Item of Short-Form Health Survey SF-36 and blood Brain-derived neurotrophic factor BDNF were used to assess the cognitive function before and after the intervention
Seventy participants aged from 50 to 80 years old with subjective cognitive impairment were randomly assigned to receive either WBE 3000 mgday in this 12-week double-blind placebo-controlled and parallel trial Neuropsychological assessments including Computerized Neurocognitive function test CNT Working Memory Test WMT Korean Mini-Mental State Examination K-MMSE Brief Cognitive Rating Scale BCRS Prospective and Retrospective Memory Questionnaire PRMQ Perceived Stress Scale PSS 36-Item of Short-Form Health Survey SF-36 and blood Brain-derived neurotrophic factor BDNF were used to assess the cognitive function before and after the intervention
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None