Ignite Creation Date:
2024-05-05 @ 11:58 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00198861
Status:
COMPLETED
Last Update Posted:
2016-08-02
First Post:
2005-09-13
Brief Title:
Neurobehavioral Model of HIV in Injection Drug Users
Sponsor:
The City College of New York
Organization:
The City College of New York
Study Overview
Official Title:
Neurobehavioral Model of HIV in Injection Drug Users
Status:
COMPLETED
Status Verified Date:
2016-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this R01 study is to evaluate the association between neuropsychological executive dysfunction and HIV infection among young injection and non-injection drug users A longitudinal study will be conducted in which the cohort of seronegative drug users completing a baseline neuropsychological battery are re-assessed on three subsequent occasions roughly six months apart The primary aim of the longitudinal study is to estimate the magnitude of the suspected causal relationship between executive dysfunction and HIV-risk behaviors while adjusting for time-invariant eg sex ethnicity and time-varying eg degree of drug abuse covariates We also seek to evaluate 1 the degree to which specific executive dysfunctions predispose heroin and cocaine users to high-risk injection practices or sex behaviors and 2 whether observed relationship between executive dysfunction and HIV-risk behaviors can be understood independent of levels of drug -taking frequency or whether the observed data are more consistent with complex patterns of interdependency between executive dysfunction drug-taking frequency and HIV-risk-behaviors If successful this project will shed new light on significant and potentially malleable HIV-risk factors in injection and non-injection drug users This will be important evidence because injection drug abuse continues to account for a large proportion of HIV seroconversions particularly among young women and minorities As such this RO1 research project serves as an important initial step in a line of innovative investigations about suspected causal associations between neuropsychological deficits and HIV-risk behaviors in drug users Ultimately this line of investigation should lead to changes in public and clinical practices designed to prevent HIV infection
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 5R01DA014498 | NIH | None | httpsreporternihgovquickSearch5R01DA014498 |