Ignite Creation Date:
2024-05-05 @ 11:58 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00198874
Status:
COMPLETED
Last Update Posted:
2012-09-28
First Post:
2005-09-13
Brief Title:
Youth Drug Abuse Family and Cognitive-Behavioral Therapy
Sponsor:
University of Florida
Organization:
University of Florida
Study Overview
Official Title:
Youth Drug Abuse Family and Cognitive-Behavioral Therapy
Status:
COMPLETED
Status Verified Date:
2012-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This Stage II study is in response to NIDAs Behavioral Therapies Development Program PA-99-107 A randomized clinical trial is proposed to evaluate the direct mediated and moderated effects of Integrated Family and Cognitive-Behavioral Therapy IFCBT a multisystems treatment for adolescent drug abuse with promising efficacy results In the first study aim we seek to evaluate the separate and possibly synergistic effects of family systems and cognitive-behavioral IFCBT components on posttreatment drug abuse problem severity problem behavior psychiatric distress and academic achievement of adolescent drug abusers Innovative analytic strategies are subsequently used to evaluate the degree to which successful outcomes are attributable to specific familial and cognitive-behavioral change processes targeted by IFCBT components The possibility of effect-modification also is considered with a focus on neurocognitive psychiatric comorbidity and demographic factors Namely we seek to understand how variations in specific client characteristics such as executive dysfunctions or psychiatric comorbidity might explain why treatments work for some drug abusing youths but not others In addition to promising findings on IFCBT efficacy this Stage II proposal benefits from the development and Stage I study application of a treatment manuals b therapist training procedures c therapist adherence and competence tools d a neuropsychological battery to assess cognitive functions e a psychodiagnostic battery to assess comorbid psychiatric disorders and f a study assessment battery comprised of therapeutic process and outcome measures This revised application has sought to address well-taken concerns cited by the reviewers while maintaining proposal strengths The lack of adolescent drug treatment research continues to be a serious gap in the addictions literature despite alarmingly high rates of drug abuse among youth and the range of morbidities and mortality that result nationwide If successful this project should help to identify specific behavior change processes targeted by family systems and cognitive-behavioral treatments that foster subsequent reductions in drug use and problem behavior among recovering youth Neurocognitive and psychiatric influences on adolescent drug treatment outcomes appear to be significant yet are poorly understood Increasing our understanding of relationships between client characteristics skill development during treatments and subsequent outcomes should also help to improve adolescent drug treatments
Detailed Description:
This Stage II study is in response to NIDAs Behavioral Therapies Development Program PA-99-107 A randomized clinical trial is proposed to evaluate the direct mediated and moderated effects of Integrated Family and Cognitive-Behavioral Therapy IFCBT a multisystems treatment for adolescent drug abuse with promising efficacy results In the first study aim we seek to evaluate the separate and possibly synergistic effects of family systems and cognitive-behavioral IFCBT components on posttreatment drug abuse problem severity problem behavior psychiatric distress and academic achievement of adolescent drug abusers Innovative analytic strategies are subsequently used to evaluate the degree to which successful outcomes are attributable to specific familial and cognitive-behavioral change processes targeted by IFCBT components The possibility of effect-modification also is considered with a focus on neurocognitive psychiatric comorbidity and demographic factors Namely we seek to understand how variations in specific client characteristics such as executive dysfunctions or psychiatric comorbidity might explain why treatments work for some drug abusing youths but not others In addition to promising findings on IFCBT efficacy this Stage II proposal benefits from the development and Stage I study application of a treatment manuals b therapist training procedures c therapist adherence and competence tools d a neuropsychological battery to assess cognitive functions e a psychodiagnostic battery to assess comorbid psychiatric disorders and f a study assessment battery comprised of therapeutic process and outcome measures This revised application has sought to address well-taken concerns cited by the reviewers while maintaining proposal strengths The lack of adolescent drug treatment research continues to be a serious gap in the addictions literature despite alarmingly high rates of drug abuse among youth and the range of morbidities and mortality that result nationwide If successful this project should help to identify specific behavior change processes targeted by family systems and cognitive-behavioral treatments that foster subsequent reductions in drug use and problem behavior among recovering youth Neurocognitive and psychiatric influences on adolescent drug treatment outcomes appear to be significant yet are poorly understood Increasing our understanding of relationships between client characteristics skill development during treatments and subsequent outcomes should also help to improve adolescent drug treatments
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 5R01DA010777-08 | NIH | None | httpsreporternihgovquickSearch5R01DA010777-08 |