Ignite Creation Date:
2024-05-05 @ 11:57 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00190281
Status:
UNKNOWN
Last Update Posted:
2005-12-13
First Post:
2005-09-13
Brief Title:
Contrast-Enhanced US of Spleen Liver and Kidney
Sponsor:
Assistance Publique - Hôpitaux de Paris
Organization:
Assistance Publique - Hôpitaux de Paris
Study Overview
Official Title:
Contrast-Enhanced US of Spleen Liver and Kidney in Patients With Acute Infection Malaria and Other Infectious Diseases a Functional Study
Status:
UNKNOWN
Status Verified Date:
2005-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To evaluate the changes in the microcirculation of the liver kidney and spleen during acute infection in patients with malaria cohorts 1 and 3 and other infectious diseases such as acute pyelonephritis at day 0 within 8 hours of the treatment start day 2 to 4 and day 28-32 using functional US with continuous infusion of a contrast agent SonoVue Bracco Italy
Study hypothesis malaria patients should exhibit a different pattern of enhancement particularly when quantitative measurements of the SU signals is performed with destruction reperfusion kinetics
Study hypothesis malaria patients should exhibit a different pattern of enhancement particularly when quantitative measurements of the SU signals is performed with destruction reperfusion kinetics
Detailed Description:
To evaluate the changes in the microcirculation of the liver kidney and spleen during acute infection in patients with malaria cohorts 1 and 3 and other infectious diseases such as acute pyelonephritis at day 0 within 8 hours of the treatment start day 2 to 4 and day 28-32 using functional US with continuous infusion of a contrast agent SonoVue Bracco Italy
Three cohortes will be studied cohorte 1 infection at Plasmodium falciparum 24 patients cohorte 3 infection at Plasmodium vivax ovale or malariae 5 patients and cohorte 2 other infectious diseases such as acute pyelonephritis 24 patients
Study hypothesis malaria patients should exhibit a different pattern of enhancement particularly when quantitative measurements of the SU signals is performed with destruction reperfusion kinetics
Three cohortes will be studied cohorte 1 infection at Plasmodium falciparum 24 patients cohorte 3 infection at Plasmodium vivax ovale or malariae 5 patients and cohorte 2 other infectious diseases such as acute pyelonephritis 24 patients
Study hypothesis malaria patients should exhibit a different pattern of enhancement particularly when quantitative measurements of the SU signals is performed with destruction reperfusion kinetics
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None