Ignite Creation Date:
2024-05-06 @ 3:58 AM
Last Modification Date:
2024-10-26 @ 11:41 AM
Study NCT ID:
NCT02415452
Status:
UNKNOWN
Last Update Posted:
2016-01-20
First Post:
2015-04-09
Brief Title:
Researches of Retinal Artery Lesions and Acute Coronary Syndrome
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
Retinal Artery Lesions to Predict Long-term Outcomes in Patients With Acute Coronary Syndrome After Drug-Eluting Stent Implantation
Status:
UNKNOWN
Status Verified Date:
2016-01
Last Known Status:
ACTIVE_NOT_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
REACS
Brief Summary:
This study is to investigate the relationship between staging of retinal artery lesions and the prognosis of acute coronary syndrome ACS in a Chinese population All the patients were divided into four groups according retinal artery lesionsThe endpoints were main adverse cardiovascular and cerebrovascular events MACCE including all-cause death myocardial infarction MI and stroke after 3 to 6 years of follow-up
Detailed Description:
The aim of this study was to determine whether retinal artery lesions can predict long-term adverse outcomes in acute coronary syndrome ACS patients after drug-eluting stent DES implant
A total of 660 consecutive patients with ACS who underwent coronary angiography and percutaneous coronary intervention enrolled this study at the Beijing Mentougou District Hospital Beijing Tiantan Hospital and Beijing Shijitan Hospital All the subjects were divided into two groups based on the retinal artery lesions Group 1 retinal artery lesions Stage 2 n296 and group 2 n364 retinal artery lesions Stage 2 Besidethe eye fundus examination was done in all patients to mesure the extent and severity of atherosclerotic vascular lesions in the retinal arteries Patients were excluded from the study if they had severe nephropathy GFR 30 mLmin173 m2 vascular obstruction acute illnesses or any other condition that was thought to contraindicated coronary angiography
Primary endpoint was all-cause mortality The composite endpoint was defined as major adverse cardiac and cerebrovascular events MACCE namely recurrent serious angina pectoris nonfatal MI revascularization and stroke
A total of 660 consecutive patients with ACS who underwent coronary angiography and percutaneous coronary intervention enrolled this study at the Beijing Mentougou District Hospital Beijing Tiantan Hospital and Beijing Shijitan Hospital All the subjects were divided into two groups based on the retinal artery lesions Group 1 retinal artery lesions Stage 2 n296 and group 2 n364 retinal artery lesions Stage 2 Besidethe eye fundus examination was done in all patients to mesure the extent and severity of atherosclerotic vascular lesions in the retinal arteries Patients were excluded from the study if they had severe nephropathy GFR 30 mLmin173 m2 vascular obstruction acute illnesses or any other condition that was thought to contraindicated coronary angiography
Primary endpoint was all-cause mortality The composite endpoint was defined as major adverse cardiac and cerebrovascular events MACCE namely recurrent serious angina pectoris nonfatal MI revascularization and stroke
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None