Ignite Creation Date:
2025-12-24 @ 12:12 PM
Ignite Modification Date:
2026-02-01 @ 9:47 AM
Study NCT ID:
NCT02364661
Status:
UNKNOWN
Last Update Posted:
2015-02-18
First Post:
2015-02-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Influence of Short-term Starvation on Hepatitis B Virus Load
Sponsor:
Rabin Medical Center
Organization:
Study Overview
Official Title:
The Influence of Short-term Starvation on Disease Severity and Viral Replication Among Hepatitis B Virus Patients
Status:
UNKNOWN
Status Verified Date:
2015-02
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Hepatitis B virus is a small DNA virus that affects 400 million people worldwide. The virus infects the liver and previous studies, done in tissue culture and in animals, have shown that viral replication is affected by metabolic changes occurring in the liver. Specifically, starvation induces HBV gene expression and replication, in parallel to the activation of the gluconeogenesis response, and feeding attenuates viral activity. In this study we are going to recruit HBV patients with detectable viremia and analyze their viral load after an over night starvation versus after a morning meal. Our hypothesis is that following an over-night starvation viral load will be higher than that in the fed state.
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: