Ignite Creation Date:
2026-03-26 @ 3:20 PM
Ignite Modification Date:
2026-03-30 @ 1:18 AM
Study NCT ID:
NCT07403305
Status:
NOT_YET_RECRUITING
Last Update Posted:
2026-02-11
First Post:
2026-01-05
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Effect of Water Physical Exercise Program in Thermal Water and Hydropinotherapy on Cardiovascular Health
Sponsor:
Instituto Politécnico de Bragança
Organization:
Study Overview
Official Title:
The Effect of Water Physical Exercise Program in Thermal Water and Hydropinotherapy on Cardiovascular Health
Status:
NOT_YET_RECRUITING
Status Verified Date:
2025-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
WPEPH
Brief Summary:
The goal of this randomized four-arm clinical trial is to determine the effect of 16-week water physical exercise program in thermal water and hydroponotherapy on lipide profile in middle-aged and elderly people, with controlled health conditions.
Participants will be randomizate into four arms:
* Arm I: Control
* Arm II: Water Physical Exercise Program (WPEP) in thermal water
* Arm III: Hydropinotherapy with thermal water combined with bay leaf (L. nobilis)
* Arm IV: WPEP in thermal water and hydropinotherapy with thermal water combined with bay leaf (L. nobilis)
Primary outcome:
1. Lipid profile (cholesterol total, low-density lipoprotein cholesterol (c-LDL), high-density lipoprotein cholesterol (c-HDL), triglycerides)
Secondary parameters:
2. Inflammatory biomarkers: interleukin-6 (IL-6), C-reactive protein (CRP)
3. Glucose metabolisc: fasting plasma glucose, insulin, Hemoglobin A1c (HbA1c)
4. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase, bilirubin, creatinine.
5. Anthropometric and clinical variables: weight, waist to hip ratio, body composition and bone mineral density
6. Systolic and diastolic blood pressure
7. Physical function
8. Lifestyle parameters: sleep quality, quality of life and eating habits
Participants will be randomizate into four arms:
* Arm I: Control
* Arm II: Water Physical Exercise Program (WPEP) in thermal water
* Arm III: Hydropinotherapy with thermal water combined with bay leaf (L. nobilis)
* Arm IV: WPEP in thermal water and hydropinotherapy with thermal water combined with bay leaf (L. nobilis)
Primary outcome:
1. Lipid profile (cholesterol total, low-density lipoprotein cholesterol (c-LDL), high-density lipoprotein cholesterol (c-HDL), triglycerides)
Secondary parameters:
2. Inflammatory biomarkers: interleukin-6 (IL-6), C-reactive protein (CRP)
3. Glucose metabolisc: fasting plasma glucose, insulin, Hemoglobin A1c (HbA1c)
4. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase, bilirubin, creatinine.
5. Anthropometric and clinical variables: weight, waist to hip ratio, body composition and bone mineral density
6. Systolic and diastolic blood pressure
7. Physical function
8. Lifestyle parameters: sleep quality, quality of life and eating habits
Detailed Description:
None
Study Oversight
Has Oversight DMC:
True
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
False
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| UIDB/00690/2020; UIDP/00690 | OTHER_GRANT | Fundação para Ciência e Tecnologia | View | |
| LA/P/0007/2020 | OTHER_GRANT | Fundação para Ciência e Tecnologia | View | |
| UIDB/00617/2020, LA/P/0064/202 | OTHER_GRANT | Fundação para Ciência e Tecnologia (FCT) | View | |
| PRT/BD/154584/2023 | OTHER_GRANT | Fundação para Ciência e Tecnologia (FCT) | View |