Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-31 @ 7:34 AM
Study NCT ID:
NCT07371858
Status:
COMPLETED
Last Update Posted:
2026-01-28
First Post:
2025-04-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
The Effect of Home-Based Exercise on Chronic Kidney Disease Patients
Sponsor:
Akdeniz University
Organization:
Study Overview
Official Title:
The Effect of Home-Based Exercise on Sarcopenia Risk, Functional Capacity, Depression, Fatigue, Sleep, and Quality of Life in Chronic Kidney Disease Patients
Status:
COMPLETED
Status Verified Date:
2026-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The aim of this study is to investigate the effects of home-based exercise on the risk of sarcopenia, functional capacity, anxiety, depression, fatigue, sleep, and quality of life in patients aged 45 and over with chronic kidney disease (Stage 4-5) who are not on dialysis.
A total of 26 voluntary participants aged 45 and above with chronic kidney disease (Stages 4-5) who are not undergoing dialysis will be included in the study. Participants will be randomly assigned to either the intervention or control group using block randomization method. While the intervention group will engage in a 12-week home exercise program, the control group will not receive any exercise intervention. The effects of the 12-week home exercise program on Sarcopenia Risk, Functional Capacity, Depression, Fatigue, Sleep, and Quality of Life will be evaluated before and after the intervention in this study.
A total of 26 voluntary participants aged 45 and above with chronic kidney disease (Stages 4-5) who are not undergoing dialysis will be included in the study. Participants will be randomly assigned to either the intervention or control group using block randomization method. While the intervention group will engage in a 12-week home exercise program, the control group will not receive any exercise intervention. The effects of the 12-week home exercise program on Sarcopenia Risk, Functional Capacity, Depression, Fatigue, Sleep, and Quality of Life will be evaluated before and after the intervention in this study.
Detailed Description:
The aim of this study is to investigate the effects of home-based exercise on sarcopenia risk, functional capacity, anxiety, depression, fatigue, sleep, and quality of life in patients aged 45 and over with chronic kidney disease (Stage 4-5) who are not undergoing dialysis.
A total of 26 patients aged 45 and over with chronic kidney disease (Stage 4-5) who are not on dialysis and followed up at the Nephrology Outpatient Clinic, Low Clearance Department of Akdeniz University Hospital, will be included in the study as voluntary participants. The study and control groups will be determined using block randomization method.
Both groups will undergo SARC-F questionnaire, anthropometric measurements, Mini Nutritional Assessment Short Form (MNA-SF), FACIT fatigue scale, Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, Kidney Disease Quality of Life Scale (KDQOL-SF), 6-minute walk test, 10-meter walk speed test, 5-repetition sit-to-stand test, handgrip strength measurement, and manual muscle strength measurements before the study (week 0). In addition to these assessments, the study group will receive a home-based exercise program for 30-55 minutes, 3-4 times a week for 12 weeks, with the intensity of exercise adjusted according to the participant's perceived exertion, and each participant will be supervised by a physiotherapist until they learn the exercises. After 12 weeks, all these questionnaires and tests will be repeated for both groups, and the results will be compared.
Additionally, in this study, a website will be designed to facilitate access to and monitoring of home-based exercise programs, enabling participants to benefit from telehealth services-a prominent topic in recent healthcare research. At the end of the intervention, the Exercise Adherence Rating Scale (EARS) will be administered to the intervention group to evaluate patients' adherence to the prescribed home exercise program, as well as the reasons for adherence or non-adherence. Through this assessment, the effectiveness of the implemented telehealth service will be measured. Therefore, this study emphasizes a personalized and comprehensive approach that not only addresses health-related outcomes but also aims to improve patients' overall quality of life.
A total of 26 patients aged 45 and over with chronic kidney disease (Stage 4-5) who are not on dialysis and followed up at the Nephrology Outpatient Clinic, Low Clearance Department of Akdeniz University Hospital, will be included in the study as voluntary participants. The study and control groups will be determined using block randomization method.
Both groups will undergo SARC-F questionnaire, anthropometric measurements, Mini Nutritional Assessment Short Form (MNA-SF), FACIT fatigue scale, Hospital Anxiety and Depression Scale, Pittsburgh Sleep Quality Index, Kidney Disease Quality of Life Scale (KDQOL-SF), 6-minute walk test, 10-meter walk speed test, 5-repetition sit-to-stand test, handgrip strength measurement, and manual muscle strength measurements before the study (week 0). In addition to these assessments, the study group will receive a home-based exercise program for 30-55 minutes, 3-4 times a week for 12 weeks, with the intensity of exercise adjusted according to the participant's perceived exertion, and each participant will be supervised by a physiotherapist until they learn the exercises. After 12 weeks, all these questionnaires and tests will be repeated for both groups, and the results will be compared.
Additionally, in this study, a website will be designed to facilitate access to and monitoring of home-based exercise programs, enabling participants to benefit from telehealth services-a prominent topic in recent healthcare research. At the end of the intervention, the Exercise Adherence Rating Scale (EARS) will be administered to the intervention group to evaluate patients' adherence to the prescribed home exercise program, as well as the reasons for adherence or non-adherence. Through this assessment, the effectiveness of the implemented telehealth service will be measured. Therefore, this study emphasizes a personalized and comprehensive approach that not only addresses health-related outcomes but also aims to improve patients' overall quality of life.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: