Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-04-06 @ 1:52 AM
Study NCT ID:
NCT07397858
Status:
NOT_YET_RECRUITING
Last Update Posted:
2026-02-09
First Post:
2025-12-11
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Cognition and Behavior With Sham Accelerated TMS
Sponsor:
University of California, Davis
Organization:
Study Overview
Official Title:
Studies of Cognition and Behavior Using Sham Accelerated Transcranial Magnetic Stimulation
Status:
NOT_YET_RECRUITING
Status Verified Date:
2026-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards. The study includes young people ages 15-25 who will complete a sham (placebo) version of an accelerated transcranial magnetic stimulation (TMS) treatment. No active brain stimulation is given.
The main questions this study aims to answer are:
1. Do expectancy and treatment beliefs change during and after an accelerated sham TMS schedule?
2. Do these expectations influence mood, reward processing, or craving?
3. Does a more intensive schedule of sham sessions lead to different expectancy effects than a slower, once-daily schedule?
Participants will:
* Complete baseline clinical assessments and an MRI session
* Undergo five days of accelerated sham TMS (no active brain stimulation is delivered)
* Complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks
The main questions this study aims to answer are:
1. Do expectancy and treatment beliefs change during and after an accelerated sham TMS schedule?
2. Do these expectations influence mood, reward processing, or craving?
3. Does a more intensive schedule of sham sessions lead to different expectancy effects than a slower, once-daily schedule?
Participants will:
* Complete baseline clinical assessments and an MRI session
* Undergo five days of accelerated sham TMS (no active brain stimulation is delivered)
* Complete post-treatment MRI and follow-up assessments at 1 week and 4 weeks
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: