Ignite Creation Date:
2026-03-26 @ 3:18 PM
Ignite Modification Date:
2026-03-30 @ 5:47 PM
Study NCT ID:
NCT07377851
Status:
COMPLETED
Last Update Posted:
2026-01-30
First Post:
2026-01-22
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Carbonic Anhydrase II Responses to Basketball-Specific High-Intensity Interval Training
Sponsor:
Karamanoğlu Mehmetbey University
Organization:
Study Overview
Official Title:
Erythrocyte Carbonic Anhydrase II as a Marker of Metabolic Adaptation to Basketball-Specific High-Intensity Interval Training
Status:
COMPLETED
Status Verified Date:
2026-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
CAII-BASKET
Brief Summary:
This study aims to examine whether erythrocyte carbonic anhydrase II can be used as a biological marker of metabolic adaptation to basketball-specific high-intensity interval training. Carbonic anhydrase II is an enzyme involved in acid-base balance and carbon dioxide transport, and it may reflect physiological adaptations to intense exercise.
Healthy basketball players participated in a structured high-intensity interval training program designed to reflect the physical demands of basketball. Blood samples and performance-related measurements were collected before and after the training period to evaluate changes in erythrocyte carbonic anhydrase II levels and related metabolic responses.
The findings of this study are expected to improve the understanding of exercise-induced metabolic adaptations and to explore the potential use of erythrocyte carbonic anhydrase II as a practical biomarker for monitoring training responses in basketball players.
Healthy basketball players participated in a structured high-intensity interval training program designed to reflect the physical demands of basketball. Blood samples and performance-related measurements were collected before and after the training period to evaluate changes in erythrocyte carbonic anhydrase II levels and related metabolic responses.
The findings of this study are expected to improve the understanding of exercise-induced metabolic adaptations and to explore the potential use of erythrocyte carbonic anhydrase II as a practical biomarker for monitoring training responses in basketball players.
Detailed Description:
This study was designed to investigate erythrocyte carbonic anhydrase II as a potential biomarker of metabolic adaptation to basketball-specific high-intensity interval training. Carbonic anhydrase II plays a key role in acid-base regulation and carbon dioxide transport, which are critical physiological processes during repeated high-intensity exercise.
Participants were healthy basketball players who completed a structured high-intensity interval training program reflecting the intermittent and high-demand nature of basketball activity. The training protocol consisted of repeated bouts of intense exercise interspersed with short recovery periods, consistent with established basketball-specific conditioning practices.
Blood samples were obtained at predefined time points to assess erythrocyte carbonic anhydrase II levels. These biochemical measurements were evaluated alongside selected performance and physiological indicators to characterize training-induced metabolic adaptations. All assessments were conducted under standardized conditions to minimize variability related to diet, hydration, and recent physical activity.
The study followed an observational pre-post design without clinical intervention beyond the prescribed training program. No experimental drugs or medical devices were used. Safety monitoring was conducted throughout the study period, and no serious adverse events were anticipated given the low-risk nature of the exercise protocol and the healthy status of the participants.
This study seeks to contribute to the growing body of research on exercise-related biomarkers by examining whether erythrocyte carbonic anhydrase II may provide practical insight into metabolic adaptation to sport-specific high-intensity training.
Participants were healthy basketball players who completed a structured high-intensity interval training program reflecting the intermittent and high-demand nature of basketball activity. The training protocol consisted of repeated bouts of intense exercise interspersed with short recovery periods, consistent with established basketball-specific conditioning practices.
Blood samples were obtained at predefined time points to assess erythrocyte carbonic anhydrase II levels. These biochemical measurements were evaluated alongside selected performance and physiological indicators to characterize training-induced metabolic adaptations. All assessments were conducted under standardized conditions to minimize variability related to diet, hydration, and recent physical activity.
The study followed an observational pre-post design without clinical intervention beyond the prescribed training program. No experimental drugs or medical devices were used. Safety monitoring was conducted throughout the study period, and no serious adverse events were anticipated given the low-risk nature of the exercise protocol and the healthy status of the participants.
This study seeks to contribute to the growing body of research on exercise-related biomarkers by examining whether erythrocyte carbonic anhydrase II may provide practical insight into metabolic adaptation to sport-specific high-intensity training.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: