Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-30 @ 10:29 PM
Study NCT ID:
NCT07436169
Status:
COMPLETED
Last Update Posted:
2026-02-27
First Post:
2026-02-21
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
2D:4D Finger Ratio and Breast Cancer in Women
Sponsor:
Malatya Turgut Ozal University
Organization:
Study Overview
Official Title:
Evaluation Of The Relationship Between Finger 2d-4d Ratios And Cancer In Breast Cancer Patients. A Randomized Controlled Trial
Status:
COMPLETED
Status Verified Date:
2024-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
This prospective study aims to evaluate the 2D:4D finger ratio in women diagnosed with breast cancer compared to healthy controls and to examine its potential association with tumor markers, including carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA 15-3).
A total of 132 women are included in the study, comprising 79 patients with breast cancer and 53 healthy controls. Participants are recruited from a breast clinic setting. Finger lengths are measured to calculate 2D:4D ratios, and serum CEA and CA 15-3 levels are recorded. Statistical analyses are performed to assess correlations between finger morphometry and tumor marker levels.
The study seeks to explore whether finger length patterns and 2D:4D ratios are associated with breast cancer status and selected tumor markers, and to evaluate their potential relevance as non-invasive indicators related to hormonal exposure history.
A total of 132 women are included in the study, comprising 79 patients with breast cancer and 53 healthy controls. Participants are recruited from a breast clinic setting. Finger lengths are measured to calculate 2D:4D ratios, and serum CEA and CA 15-3 levels are recorded. Statistical analyses are performed to assess correlations between finger morphometry and tumor marker levels.
The study seeks to explore whether finger length patterns and 2D:4D ratios are associated with breast cancer status and selected tumor markers, and to evaluate their potential relevance as non-invasive indicators related to hormonal exposure history.
Detailed Description:
Breast cancer is one of the most common malignancies among women worldwide. Prenatal hormonal exposure has been proposed as a potential factor influencing the development of hormone-related cancers. The second-to-fourth digit (2D:4D) ratio is considered an indirect marker of prenatal androgen and estrogen exposure and has been investigated in relation to various health conditions.
This prospective study is designed to evaluate differences in 2D:4D finger ratios between women diagnosed with breast cancer and healthy controls and to examine potential associations between digit ratios and tumor markers, including carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA 15-3).
A total of 132 women are included in the study, consisting of 79 breast cancer patients and 53 healthy controls recruited from a breast clinic setting. Finger lengths of both hands are measured to calculate 2D:4D ratios. Serum CEA and CA 15-3 levels are recorded as part of routine clinical evaluation.
Statistical analyses are conducted to assess correlations between finger measurements, digit ratios, and tumor marker levels. The study aims to explore whether finger morphometry may provide additional insight into hormonal exposure patterns and their potential relevance in breast cancer assessment.
This prospective study is designed to evaluate differences in 2D:4D finger ratios between women diagnosed with breast cancer and healthy controls and to examine potential associations between digit ratios and tumor markers, including carcinoembryonic antigen (CEA) and cancer antigen 15-3 (CA 15-3).
A total of 132 women are included in the study, consisting of 79 breast cancer patients and 53 healthy controls recruited from a breast clinic setting. Finger lengths of both hands are measured to calculate 2D:4D ratios. Serum CEA and CA 15-3 levels are recorded as part of routine clinical evaluation.
Statistical analyses are conducted to assess correlations between finger measurements, digit ratios, and tumor marker levels. The study aims to explore whether finger morphometry may provide additional insight into hormonal exposure patterns and their potential relevance in breast cancer assessment.
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| B.270 | OTHER_GRANT | Malatya Turgut Ozal University Ethical Commitee | View |