Ignite Creation Date:
2026-03-26 @ 3:17 PM
Ignite Modification Date:
2026-03-31 @ 10:59 AM
Study NCT ID:
NCT07341269
Status:
COMPLETED
Last Update Posted:
2026-01-14
First Post:
2025-12-20
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Urinary NGAL and KIM-1 After ESWL
Sponsor:
Marmara University
Organization:
Study Overview
Official Title:
Prospective Evaluation of the Effect of Different Intervals Between Extracorporeal Shock Wave Lithotripsy (ESWL) Sessions on Potential Renal Injury Using Urinary NGAL and KIM-1 Biomarkers
Status:
COMPLETED
Status Verified Date:
2026-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with urinary system stone disease.
The main questions it aims to answer are:
Does the interval between consecutive ESWL sessions affect the degree of renal injury?
Are urinary NGAL and KIM-1 levels reliable biomarkers for detecting ESWL-related renal damage?
What is the optimal time interval between ESWL sessions to minimize renal injury?
If there is a comparison group, researchers will compare patients undergoing ESWL with different inter-session time intervals to determine whether shorter or longer intervals are associated with higher levels of renal injury biomarkers.
Participants will:
Undergo ESWL treatment for urinary system stones
Be assigned to one of two groups based on the time interval between ESWL sessions
Provide urine samples before ESWL and after three ESWL sessions
Have urinary NGAL and KIM-1 levels measured to assess renal injury
The main questions it aims to answer are:
Does the interval between consecutive ESWL sessions affect the degree of renal injury?
Are urinary NGAL and KIM-1 levels reliable biomarkers for detecting ESWL-related renal damage?
What is the optimal time interval between ESWL sessions to minimize renal injury?
If there is a comparison group, researchers will compare patients undergoing ESWL with different inter-session time intervals to determine whether shorter or longer intervals are associated with higher levels of renal injury biomarkers.
Participants will:
Undergo ESWL treatment for urinary system stones
Be assigned to one of two groups based on the time interval between ESWL sessions
Provide urine samples before ESWL and after three ESWL sessions
Have urinary NGAL and KIM-1 levels measured to assess renal injury
Detailed Description:
None
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?: