Ignite Creation Date:
2026-03-26 @ 3:15 PM
Ignite Modification Date:
2026-03-31 @ 4:28 AM
Study NCT ID:
NCT07430566
Status:
NOT_YET_RECRUITING
Last Update Posted:
2026-02-24
First Post:
2026-02-18
Is NOT Gene Therapy:
True
Has Adverse Events:
False
Brief Title:
Trauma Exposure and Suicidal Behaviors in Adolescents Aged 11-17 Hospitalized in Child and Adolescent Psychiatry
Sponsor:
University Hospital, Montpellier
Organization:
Study Overview
Official Title:
Trauma Exposure and Suicidal Behaviors in Adolescents Aged 11-17 Hospitalized in Child and Adolescent Psychiatry
Status:
NOT_YET_RECRUITING
Status Verified Date:
2026-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
ATTAQ
Brief Summary:
It is a comparative monocentric study with longitudinal follow-up at 6 months in adolescents aged between 11 years and 17 years inclusive admitted to complete hospitalization either for suicidal behaviors or for other psychiatric causes. The objective is to explore the experiences of hospitalized adolescents regarding hospitalization, as well as their perceptions of the factors involved in their remission and their experience of the traumatic event(s) if they have been exposed.
Detailed Description:
Suicidal behaviors among adolescents are a major public health issue. Traumatic exposure (sexual abuse, violence, serious accidents) is a recognized risk factor for psychopathology and suicidality, but its precise links with suicide recurrence, comorbid psychopathology, and neurodevelopmental vulnerability remain little studied.
Hypotheses:
* Traumatic exposure is more common among suicidal adolescents than non-suicidal.
* It is associated with an increased risk of recurrence within 6 months.
* The neurodevelopmental load, irritability, PTSD and lack of resilience factors modulate this risk.
* Specific inflammatory biological profiles could be associated with suicidality.
Originality and innovative aspects:
* Multidimensional approach: clinical, psychometric, biological and qualitative.
* Constitution of a biobank for future analyses (inflammatory, genetic, epigenetic).
* Inclusion of a qualitative component exploring the subjective experience of hospitalized adolescents.
* Integrated analysis of risk, protective and biological factors to guide personalized prevention.
The main objective is to compare the frequency of traumatic exposure history evaluated with the validated questionnaire in French of the CPC version child, among adolescents aged between 11 years old and 17 years inclusive admitted to hospital, either for suicidal behaviors (suicide group), either for other psychiatric causes without a history of suicidal behavior (non-suicidal group).
Hypotheses:
* Traumatic exposure is more common among suicidal adolescents than non-suicidal.
* It is associated with an increased risk of recurrence within 6 months.
* The neurodevelopmental load, irritability, PTSD and lack of resilience factors modulate this risk.
* Specific inflammatory biological profiles could be associated with suicidality.
Originality and innovative aspects:
* Multidimensional approach: clinical, psychometric, biological and qualitative.
* Constitution of a biobank for future analyses (inflammatory, genetic, epigenetic).
* Inclusion of a qualitative component exploring the subjective experience of hospitalized adolescents.
* Integrated analysis of risk, protective and biological factors to guide personalized prevention.
The main objective is to compare the frequency of traumatic exposure history evaluated with the validated questionnaire in French of the CPC version child, among adolescents aged between 11 years old and 17 years inclusive admitted to hospital, either for suicidal behaviors (suicide group), either for other psychiatric causes without a history of suicidal behavior (non-suicidal group).
Study Oversight
Has Oversight DMC:
False
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
Secondary ID Infos
| Secondary ID | Type | Domain | Link | View |
|---|---|---|---|---|
| 2025-A02017-42 | OTHER | ANSM | View |