Ignite Creation Date:
2024-05-06 @ 3:47 AM
Last Modification Date:
2024-10-26 @ 11:39 AM
Study NCT ID:
NCT02377206
Status:
COMPLETED
Last Update Posted:
2022-09-14
First Post:
2015-02-17
Brief Title:
Neuroinflammation and Cognitive Decline in Alzheimer Disease
Sponsor:
University Hospital Tours
Organization:
University Hospital Tours
Study Overview
Official Title:
Neuroinflammation and Cognitive Decline in Alzheimer Disease AD Pilot Study of Translocator Proteins Ligand PET Imaging With 18FDPA-714
Status:
COMPLETED
Status Verified Date:
2022-09
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
NICAD
Brief Summary:
The purpose of this study is to assess the level of neuroinflammation in Alzheimer Disease subject mild to moderate estimated with Binding Potential BP of 18FDPA-714 and its relationship with the kinetics of cognitive decline over a 24-month follow-up period as assessed by Alzheimers Disease Assessment Scale-cognitive subscale ADAS-Cog and Mini-Mental State Examination MMSE scores
Detailed Description:
The purpose of this study is to assess the level of neuroinflammation in Alzheimer Disease subject mild to moderate estimated with Binding Potential BP of 18FDPA-714 and its relationship with the kinetics of cognitive decline over a 24-month follow-up period as assessed by ADAS-Cog and MMSE scores
DPA-714 NN-diethyl-2-4-2-fluoroethoxyphenyl-57-dimethylpyrazolo15-apyrimidine-3-acetamide
DPA-714 NN-diethyl-2-4-2-fluoroethoxyphenyl-57-dimethylpyrazolo15-apyrimidine-3-acetamide
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None