Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00181792
Status:
COMPLETED
Last Update Posted:
2012-05-04
First Post:
2005-09-13
Brief Title:
Family Risk Analysis of Substance Use in Attention Deficit Hyperactivity Disorder ADHD Youth Treated With Concerta
Sponsor:
Massachusetts General Hospital
Organization:
Massachusetts General Hospital
Study Overview
Official Title:
Family Risk Analysis of Substance Use in ADHD Youth Treated With Concerta
Status:
COMPLETED
Status Verified Date:
2012-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The researchers will study 100 families over three years each with a child proband between the ages of 12-17 with the Diagnostic and Statistical Manual of Mental Disorders Fourth Edition DSM-IV diagnosis of ADHD The researchers hypothesize smoking will be familial and ADHD probands with a family history of tobacco use will be at increased risk for early initiation and persistence of smoking compared to ADHD probands with no family history of tobacco use
Detailed Description:
As Attention Deficit Hyperactivity Disorder ADHD is a documented risk factor for smoking in adolescents and as theoretical considerations suggest that ADHD and tobacco use may share common underlying mechanisms the proposed study looks to examine the association between smoking and ADHD Since both ADHD and smoking are known to be familial disorders one approach to examine the nature of the association between the two disorders is to conduct a familial risk analysis comparing ADHD youth who smoke and ADHD youth who dont smoke Another approach is to conduct a genetic study to identify candidate genes associated with nicotine abuse and dependence in ADHD youth and relatives
This study includes
1 assessment of psychopathology and substance usedependence
2 assessment of the family environment and
3 assessment of molecular genetics in 100 families with at least one child proband between the ages of 12-17 with a DSM-IV diagnosis of ADHD
This study includes
1 assessment of psychopathology and substance usedependence
2 assessment of the family environment and
3 assessment of molecular genetics in 100 families with at least one child proband between the ages of 12-17 with a DSM-IV diagnosis of ADHD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None