Ignite Creation Date:
2024-05-06 @ 3:43 AM
Last Modification Date:
2024-10-26 @ 11:37 AM
Study NCT ID:
NCT02352272
Status:
COMPLETED
Last Update Posted:
2015-02-02
First Post:
2015-01-19
Brief Title:
Benefits of Sleep Extension on Performances During Total Sleep Deprivation BankingSleep
Sponsor:
Institut de Recherche Biomedicale des Armees
Organization:
Institut de Recherche Biomedicale des Armees
Study Overview
Official Title:
Benefits of Sleep Extension on Cognitive and Physical Performances During Baseline Total Sleep Deprivation and Recovery BankingSleep
Status:
COMPLETED
Status Verified Date:
2015-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
BankingSleep
Brief Summary:
Objectives investigate the effects of 6 nights of sleep extension on physical and cognitive performances before during total sleep deprivation 39 hours continuous awaking and after a subsequent recovery sleep
Design Subjects participated in two experimental conditions randomized cross-over design extended sleep 10-h in bed EXT and habitual sleep 8-h in bed HAB In each condition subjects performed two consecutive phases 1 six nights of either EXT or HAB 2 three experiments days in-laboratorybaseline BASE sleep deprivation TSD and after 10 h of recovery sleepREC Performance tests were administered every 3 hours over the 3-d in laboratory
Setting This cross-over and randomized study was conducted under standardized laboratory conditions with continuous polysomnographic recording Participants 14 healthy men age range 26-37 years participated in the study
Interventions EXT vs HAB sleep durations prior to total sleep deprivation 39 hr continuous awaking
Design Subjects participated in two experimental conditions randomized cross-over design extended sleep 10-h in bed EXT and habitual sleep 8-h in bed HAB In each condition subjects performed two consecutive phases 1 six nights of either EXT or HAB 2 three experiments days in-laboratorybaseline BASE sleep deprivation TSD and after 10 h of recovery sleepREC Performance tests were administered every 3 hours over the 3-d in laboratory
Setting This cross-over and randomized study was conducted under standardized laboratory conditions with continuous polysomnographic recording Participants 14 healthy men age range 26-37 years participated in the study
Interventions EXT vs HAB sleep durations prior to total sleep deprivation 39 hr continuous awaking
Detailed Description:
Many human endeavors require high-level cognitive performance situations eg health care military operations space flight along the whole nycthemera ie the 24-h cycle
It has long been established that both acute total sleep deprivation TSD and chronic sleep restriction impair ability to maintain wakefulness increase subjective sleepiness and sleep propensity and most critically reduce various aspects of cognitive performance In studies conducted in both laboratory setting and different professional situations inducing insufficient sleep the most consistently and dramatically impacted cognitive capacities were sustained attention and alertness This degradation of cognitive performance after a period of sleep deprivation is linked to an increase of sleep pressure eg a reduction in the latency to sleep onset or increase of number of involuntary micro sleeps
To identify countermeasures to deleterious effects of sleep deprivation is critical in many professional areas
Management of wakesleep cycle appears to have an important impact of alertness during sleep deprivation eg sleep habits or physical activity see the review Recently Rupp and coll 2012 reported that one week of sleep extension realized before one week of sleep restriction 3 hnight influence the rate of degradation of cognitive performance and alertness during this period and the subsequent recovery period In other words they proposed that sleep can be banked before a period of sleep loss and may help sustain performance and alertness With a different experimental paradigm ie without subsequent sleep deprivation studies have shown that sleep extension realized over different periods of time may improve physical performance attentional performance or mood The fact of increasing total sleep time over a period of time represents an attractive non-pharmacological countermeasure to limit the deleterious effects on performance induced by sleep privation However there is no study with cross-over and randomized design to assess effect on relatively short period 6 nights of sleep extension on performance before during total sleep deprivation and recovery Moreover there is no direct measurement of sleep pressure as continuous EEG monitoring to quantify micro sleep episode during period of sleep deprivation and effect of sleep extension on physical performance is not known
Hence the aim of this study was to assess the effects of 6 nights of sleep extension EXT on physical and cognitive performances alertness and homeostatic sleep pressure before during total sleep deprivation and the subsequent recovery day
The investigators hypothesized that EXT would i partly prevents the physical and cognitive performances degradation-induced by total sleep deprivation ii decreases the sleep pressure before during and after total sleep deprivation and iii improves the recovery speed of physical and cognitive performances
It has long been established that both acute total sleep deprivation TSD and chronic sleep restriction impair ability to maintain wakefulness increase subjective sleepiness and sleep propensity and most critically reduce various aspects of cognitive performance In studies conducted in both laboratory setting and different professional situations inducing insufficient sleep the most consistently and dramatically impacted cognitive capacities were sustained attention and alertness This degradation of cognitive performance after a period of sleep deprivation is linked to an increase of sleep pressure eg a reduction in the latency to sleep onset or increase of number of involuntary micro sleeps
To identify countermeasures to deleterious effects of sleep deprivation is critical in many professional areas
Management of wakesleep cycle appears to have an important impact of alertness during sleep deprivation eg sleep habits or physical activity see the review Recently Rupp and coll 2012 reported that one week of sleep extension realized before one week of sleep restriction 3 hnight influence the rate of degradation of cognitive performance and alertness during this period and the subsequent recovery period In other words they proposed that sleep can be banked before a period of sleep loss and may help sustain performance and alertness With a different experimental paradigm ie without subsequent sleep deprivation studies have shown that sleep extension realized over different periods of time may improve physical performance attentional performance or mood The fact of increasing total sleep time over a period of time represents an attractive non-pharmacological countermeasure to limit the deleterious effects on performance induced by sleep privation However there is no study with cross-over and randomized design to assess effect on relatively short period 6 nights of sleep extension on performance before during total sleep deprivation and recovery Moreover there is no direct measurement of sleep pressure as continuous EEG monitoring to quantify micro sleep episode during period of sleep deprivation and effect of sleep extension on physical performance is not known
Hence the aim of this study was to assess the effects of 6 nights of sleep extension EXT on physical and cognitive performances alertness and homeostatic sleep pressure before during total sleep deprivation and the subsequent recovery day
The investigators hypothesized that EXT would i partly prevents the physical and cognitive performances degradation-induced by total sleep deprivation ii decreases the sleep pressure before during and after total sleep deprivation and iii improves the recovery speed of physical and cognitive performances
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2013-A01403-42 | OTHER | ANSM ID RCB | None |