Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00184899
Status:
COMPLETED
Last Update Posted:
2007-03-01
First Post:
2005-09-12
Brief Title:
The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids
Sponsor:
Radboud University Medical Center
Organization:
Radboud University Medical Center
Study Overview
Official Title:
The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids
Status:
COMPLETED
Status Verified Date:
2007-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The metabolic syndrome is associated with hyperdynamic circulation and sympathetic activation Recently Bakker et al Atherosclerosis 2002 described the hypothesis that free fatty acids are responsible for this association The investigators hypothesize that in patients with obesity and the metabolic syndrome an increased intracellular concentration of long-chain fatty acyl LCFA-CoA the intracellular equivalent of free fatty acids induces an increase in adenosine Adenosine receptor stimulation in turn induces vasodilation and sympathetic activation
The investigators aimed to assess this effect of free fatty acids on the adenosine system in healthy volunteers
The investigators aimed to assess this effect of free fatty acids on the adenosine system in healthy volunteers
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| ZonMw Nr 920-03-249 | None | None | None |