Ignite Creation Date:
2024-05-06 @ 3:41 AM
Last Modification Date:
2024-10-26 @ 11:36 AM
Study NCT ID:
NCT02342028
Status:
UNKNOWN
Last Update Posted:
2015-01-26
First Post:
2015-01-12
Brief Title:
The Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
Sponsor:
Taipei Veterans General Hospital Taiwan
Organization:
Taipei Veterans General Hospital Taiwan
Study Overview
Official Title:
Impact of Intermittent Hypoxia on the Number and Function of Regular T Cell in Patients With Obstructive Sleep Apnea
Status:
UNKNOWN
Status Verified Date:
2015-01
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To compare the number and function of regular T cell of patients with obstructive sleep apnea OSA versus that of age- gender- and BMI body mass index-matched controls
Detailed Description:
Patients with obstructive sleep apnea OSA experience intermittent hypoxemia and arousal during sleep due to recurrent collapse of upper airway Epidemiologic evidence showed they were at higher risk for autoimmune diseases The regular T cell Treg has a crucial role in controlling autoimmunity In this study 40 OSA patients and 40 age- gender- and BMI-matched controls will be recruited Peripheral venous blood of the participants is drawn for numeration of CD4CD25FoxP3 regular T cells by flow cytometry As well the CD4CD25 regular T cells are enriched by MACS and tested for their suppressive functions on proliferation assays Th12 CD4 cells are also measured
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None