Ignite Creation Date:
2024-05-05 @ 11:56 AM
Last Modification Date:
2024-10-26 @ 9:17 AM
Study NCT ID:
NCT00186797
Status:
COMPLETED
Last Update Posted:
2010-04-09
First Post:
2005-09-09
Brief Title:
Purified CD34 Hematopoietic Stem Cell Transplantation From Alternate Donors for Patients With Severe Aplastic Anemia
Sponsor:
St Jude Childrens Research Hospital
Organization:
St Jude Childrens Research Hospital
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2010-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
No
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AACD34
Brief Summary:
This study is for patients with Severe Aplastic Anemia SAA A stem cell transplant from a genetically matched sibling donor can help or cure this disease in 85 to 100 percent of patients Stem cells are immature blood cells that grow to become red blood cells white blood cells or platelets A genetic match means a brother or sister has same immune type HLA type as the patient Unfortunately few patients have a matched sibling donor The chance of negative outcomes is much higher with other types of donors
This study will test the success of a new approach to stem cell transplant for SAA Patients in this study will receive drugs and radiation treatment to destroy their diseased bone marrow and to prepare them for stem cell transplant Bone marrow is the tissue inside the bones where stem cells are madeStem cells will be harvested from the blood or bone marrow of genetically matched unrelated donors or partially matched family donors The stem cells will be filtered using a new device that is currently under study The patients will receive large doses of the filtered stem cells stem cell graft Researchers want to find out how the study treatment affects patients the disease and the chances for survival
This study will test the success of a new approach to stem cell transplant for SAA Patients in this study will receive drugs and radiation treatment to destroy their diseased bone marrow and to prepare them for stem cell transplant Bone marrow is the tissue inside the bones where stem cells are madeStem cells will be harvested from the blood or bone marrow of genetically matched unrelated donors or partially matched family donors The stem cells will be filtered using a new device that is currently under study The patients will receive large doses of the filtered stem cells stem cell graft Researchers want to find out how the study treatment affects patients the disease and the chances for survival
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None