Ignite Creation Date:
2024-05-06 @ 3:38 AM
Last Modification Date:
2024-10-26 @ 11:36 AM
Study NCT ID:
NCT02333916
Status:
TERMINATED
Last Update Posted:
2015-09-23
First Post:
2014-12-30
Brief Title:
Effect of Exercise and Training on Fat Oxidation During Overfeeding - the FeedEX Study
Sponsor:
Maastricht University Medical Center
Organization:
Maastricht University Medical Center
Study Overview
Official Title:
Effects of Short-term Overfeeding With or Without Exercise on 24-hour Fat Oxidation and Fat Balance Before and After 10 Weeks of Training - The FeedEX Study
Status:
TERMINATED
Status Verified Date:
2015-04
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Recruitment target could not be met
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
FeedEX
Brief Summary:
Rationale Body weight is not well regulated in all individuals In an obesogenic environment where overeating is common some individuals are more prone to weight gain and therefore overweight than others Yet the reasons behind this are unclear Resistant individuals often have higher physical activity levels PALs It seems that - at higher levels of physical activity and therefore energy expenditure - satiety signals are more precisely regulated making one better at matching energy intake with expenditure In other words active people may not overeat where sedentary people would However this does not explain the differences in weight gain observed when subjects all have to overeat imposed overfeeding It could be that active people are better able to cope metabolically with the extra calories because of already higher levels of carbohydrate and fat oxidation compared to their inactive counterparts
Objectives 1 To study the effects of overfeeding normal diet composition on substrate balance and oxidation and more specifically fat balance and oxidation 2 to study the effects of exercise and training on fat oxidation during overfeeding normal diet composition
Study design This controlled intervention study will follow a cross-over design Each subject will spend 5 nights and 4 days in a respiration chamber on two occasions separated by a 10-week training period
Objectives 1 To study the effects of overfeeding normal diet composition on substrate balance and oxidation and more specifically fat balance and oxidation 2 to study the effects of exercise and training on fat oxidation during overfeeding normal diet composition
Study design This controlled intervention study will follow a cross-over design Each subject will spend 5 nights and 4 days in a respiration chamber on two occasions separated by a 10-week training period
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None