Ignite Creation Date:
2024-05-06 @ 3:38 AM
Last Modification Date:
2024-10-26 @ 11:36 AM
Study NCT ID:
NCT02332941
Status:
COMPLETED
Last Update Posted:
2015-06-03
First Post:
2014-10-28
Brief Title:
Treatment -Resistant Neovascular Age-Related Macular Degeneration
Sponsor:
Washington University School of Medicine
Organization:
Washington University School of Medicine
Study Overview
Official Title:
Intravitreal Rituximab
Status:
COMPLETED
Status Verified Date:
2015-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
Rituximab
Brief Summary:
The purpose of this study is to determine if treatment of Age Related Macular Degeneration AMD with a new medicationrituximab is effective To address this issue investigators propose a clinical trial in which patients with late stage disease poor vision and who have failed treatment by conventional means will receive rituximab by direct injection into the affected eye and will be followed for improvement in the structure of their retina Age Related Macular Degeneration AMD is a leading cause of vision loss in the elderly with routine care involving injections in the eye to improve and to prevent worsening of vision However some patients do not respond to the medications that we currently have and as such an alternative medication is needed One potential medication is rituximab which has been injected into the eye for primary eye cancer and has been tolerated well and led to patient improvement Investigators will obtain baseline eye tests then plan on injecting this medication in to the eye of our patients with late stage AMD by first placing numbing drops into the eye then injecting the medication directly into the eye using sterile techniques Investigators will then follow the patient and repeat eye tests to monitor for improvements
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None