Ignite Creation Date:
2024-05-06 @ 3:35 AM
Last Modification Date:
2024-10-26 @ 11:35 AM
Study NCT ID:
NCT02322385
Status:
COMPLETED
Last Update Posted:
2017-03-03
First Post:
2014-01-24
Brief Title:
Clinical Implications of DNA Analysis on ADPKD
Sponsor:
Kyorin University
Organization:
Kyorin University
Study Overview
Official Title:
Mutational Types and Phenotypes Relationship in Autosomal Dominant Polycystic Kidney Disease
Status:
COMPLETED
Status Verified Date:
2017-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
DNAAA
Brief Summary:
Autosomal dominant polycystic kidney disease ADPKD is an inherited disease We plan DNA analysis using the next generation sequencer NGS and examine the relationship between mutational types and clinical phenotypes The accuracy of DNA analysis with NGS is tested by Sangers method The kidney and life survival curves will be compared between PKD1 PKD2 and non-ADPKD family members
Detailed Description:
80 unrelated patients with ADPKD attending to the Kyorin University Hospital whose clinical data are compiled DNA analysis is performed at Otsuka Pharmaceutical Laboratory
Clinical data include total kidney volume TKV TKV slope eGFR eGFR slope and other clinically relevant data
Clinical data include total kidney volume TKV TKV slope eGFR eGFR slope and other clinically relevant data
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None