Ignite Creation Date:
2024-05-06 @ 3:32 AM
Last Modification Date:
2024-10-26 @ 11:35 AM
Study NCT ID:
NCT02317718
Status:
UNKNOWN
Last Update Posted:
2014-12-16
First Post:
2014-12-09
Brief Title:
Serum Vitamin D Level and Its Association With Ovarian Reserve and IVF Outcome
Sponsor:
Fakih IVF Fertility Center
Organization:
Fakih IVF Fertility Center
Study Overview
Official Title:
Serum Vitamin D Level in Subfertile Women and Its Association With Ovarian Reserve and IVF Outcome
Status:
UNKNOWN
Status Verified Date:
2014-12
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Vitamin D has a major play in bone and calcium metabolism Vitamin D deficiency below 20 ngml has also been linked to adverse health outcomes such as malignancy cardiovascular disease immune functioning and glucose metabolism Recent data from retrospective and prospective trials have demonstrated contradictive results concerning the role of vitamin D in female reproduction and IVF outcome Some studies have found that women deficient in vitamin D had lower ovarian reserve and significantly lower clinical pregnancy rates when compared to patients who were sufficient levels in vitamin D Some studies also demonstrated that serum 25-OH-D3 levels correlates with antimullerian hormone AMH levels in women of advanced reproductive age It may also have a role to play in endocrine dysfunction and abnormal folliculogenesis in polycystic ovaries
The aim of this prospective cohort study including infertile women undergoing IVF treatment is to investigate the association between serum 25-OH- D3 levels and parametres of ovarian reserve AMH antral follicle count number of oocytes collected and clinical pregnancy and miscarriage rates
The aim of this prospective cohort study including infertile women undergoing IVF treatment is to investigate the association between serum 25-OH- D3 levels and parametres of ovarian reserve AMH antral follicle count number of oocytes collected and clinical pregnancy and miscarriage rates
Detailed Description:
Vitamin D has a major play in bone and calcium metabolism Vitamin D deficiency below 20 ngml has also been linked to adverse health outcomes such as malignancy cardiovascular disease immune functioning and glucose metabolism Recent data from retrospective and prospective trials have demonstrated contradictive results concerning the role of vitamin D in female reproduction and IVF outcome Some studies have found that women deficient in vitamin D had lower ovarian reserve and significantly lower clinical pregnancy rates when compared to patients who were sufficient levels in vitamin D Some studies also demonstrated that serum 25-OH-D3 levels correlates with antimullerian hormone AMH levels in women of advanced reproductive age It may also have a role to play in endocrine dysfunction and abnormal folliculogenesis in polycystic ovaries
The aim of this prospective cohort study including infertile women undergoing IVF treatment is to investigate the association between serum 25-OH- D3 levels and parametres of ovarian reserve AMH antral follicle count number of oocytes collected and clinical pregnancy and miscarriage rates
The aim of this prospective cohort study including infertile women undergoing IVF treatment is to investigate the association between serum 25-OH- D3 levels and parametres of ovarian reserve AMH antral follicle count number of oocytes collected and clinical pregnancy and miscarriage rates
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None