Ignite Creation Date:
2024-05-06 @ 3:32 AM
Last Modification Date:
2024-10-26 @ 11:35 AM
Study NCT ID:
NCT02315924
Status:
UNKNOWN
Last Update Posted:
2016-07-21
First Post:
2014-12-02
Brief Title:
Combined Coronary and Cerebral Angiography and Intervention for Coronary and Cerebrovascular Atherosclerosis
Sponsor:
Capital Medical University
Organization:
Capital Medical University
Study Overview
Official Title:
An Open-label Single-centre Study Evaluating the Prevalence and Characteristics of Coronary and Cerebrovascular Arteriosclerosis as Measured by Combined Coronary and Cerebral Angiography and Comparing the Efficacy and Safety of Simultaneous or Staged Coronary and Cerebral Interventional Strategy in Chinese Patients
Status:
UNKNOWN
Status Verified Date:
2016-07
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Intracranial atherosclerosis is common vascular lesion in Asian acute stroke patients and intracranial atherosclerosis patients have high rate of coronary artery disease CAD Moreover several studies showed obvious association of CAD and cerebrovascular stenosis which had been proved to increase the risk of stroke after coronary revascularization including coronary bypass surgery or percutaneous coronary intervention In addition the efficacy and safety of combined coronary and cerebral intervention are not fully investigated Hence the aim of this study is to evaluate the prevalence and characteristics of coronary and cerebrovascular arteriosclerosis as measured by combined coronary and cerebral angiography explore the relationship between inflammation atherosclerosis-related markers and coronary and cerebral atherosclerosis and compare the efficacy and safety of simultaneous or staged coronary and cerebral interventional strategy in Chinese Patients
The coronary angiography and cerebrovascular angiography are performed for all participants The combined strategy for coronary and cerebrovascular angiography is carried out routinely in the investigators institutions Simultaneous strategy is considered as that performed via the same access and within the same day Staged strategy is intended as that performed within 7 days from the first procedure The sequence of angiographies is established on an individual patient basis by the cardiovascular and neurointerventional team according to clinical symptoms of the patients and after coronary or cerebrovascular angiography After combined coronary and cerebral angiography simultaneous or staged interventional strategy will be performed in patients with severe coronary and cerebral stenosis Blood sample is obtained from artery sheath when performing coronary or cerebral angiography Lipid levels inflammation and atherosclerosis-related markers will be measured in this study
The coronary angiography and cerebrovascular angiography are performed for all participants The combined strategy for coronary and cerebrovascular angiography is carried out routinely in the investigators institutions Simultaneous strategy is considered as that performed via the same access and within the same day Staged strategy is intended as that performed within 7 days from the first procedure The sequence of angiographies is established on an individual patient basis by the cardiovascular and neurointerventional team according to clinical symptoms of the patients and after coronary or cerebrovascular angiography After combined coronary and cerebral angiography simultaneous or staged interventional strategy will be performed in patients with severe coronary and cerebral stenosis Blood sample is obtained from artery sheath when performing coronary or cerebral angiography Lipid levels inflammation and atherosclerosis-related markers will be measured in this study
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None