Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00178360
Status:
COMPLETED
Last Update Posted:
2011-08-22
First Post:
2005-09-12
Brief Title:
Effects of Music Therapy on Huntingtons Disease
Sponsor:
University of Rochester
Organization:
University of Rochester
Study Overview
Official Title:
The Effects of Music Therapy on Depression Chorea and Other Symptoms of Huntingtons Disease
Status:
COMPLETED
Status Verified Date:
2011-08
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is primarily to assess the ability of a music therapy program to improve holistically the psychological somatic and social symptoms of patients with Huntington s disease HD We hope to demonstrate the benefits of applying music therapy interventions to the management methods of HD thus paving the way for the development of an effective music therapy program for individuals with HD
Detailed Description:
ABSTRACT
Background Recent studies show that music therapy helps improve the symptomatic manifestations of Parkinsons Disease Few studies have looked at music therapy as a treatment for the psychiatric cognitive and motor symptoms of patients with Huntingtons disease HD
Objective To examine the feasibility and tolerability of a treatment program of music therapy for patients with Huntingtons disease Also to determine if music therapy improves the mood and motor features of HD while improving quality of life
Methods Subjects with HD were recruited to participate in a six-week study that included one individual half-hour music therapy session and one hour-long group session per week The music therapy protocols were adapted from the Colorado State Universitys Neurological Music Therapy program and were targeted to HD symptoms including balance and posture fine motor skills memory and attention vocalizations and mood In particular the protocols included Rhythmic Auditory Stimulation RAS Pattern Sensory Enhancement PSE and Therapeutic Instrumental Music Playing TIMP Primary outcome of tolerability was to be assessed by the subjects adherence to the therapeutic protocol attendance and the results of an exit survey inquiring about their feelings toward the use of music therapy in HD A secondary outcome of the study was the change in the Unified Huntingtons Disease Rating Scale UHDRS score between baseline and study completion
Results Five subjects were recruited for study participation one female and four males Music therapy was found to be a tolerable and feasible treatment for patients with HD 100 adherence and 98 attendance Exit surveys demonstrated strongly positive feelings towards the music therapy treatment program in four of the five subjects one survey was completed with contradictory answers by the subject While there was improvement in UHDRS scores for finger tapping pronationsupination and the Luria these changes did not achieve statistical significance with the small sample size in this study
Conclusions Music therapy was well tolerated among subjects with HD in this small study Future studies are now being planned to look at the efficacy of this intervention in a larger population of HD subjects
Background Recent studies show that music therapy helps improve the symptomatic manifestations of Parkinsons Disease Few studies have looked at music therapy as a treatment for the psychiatric cognitive and motor symptoms of patients with Huntingtons disease HD
Objective To examine the feasibility and tolerability of a treatment program of music therapy for patients with Huntingtons disease Also to determine if music therapy improves the mood and motor features of HD while improving quality of life
Methods Subjects with HD were recruited to participate in a six-week study that included one individual half-hour music therapy session and one hour-long group session per week The music therapy protocols were adapted from the Colorado State Universitys Neurological Music Therapy program and were targeted to HD symptoms including balance and posture fine motor skills memory and attention vocalizations and mood In particular the protocols included Rhythmic Auditory Stimulation RAS Pattern Sensory Enhancement PSE and Therapeutic Instrumental Music Playing TIMP Primary outcome of tolerability was to be assessed by the subjects adherence to the therapeutic protocol attendance and the results of an exit survey inquiring about their feelings toward the use of music therapy in HD A secondary outcome of the study was the change in the Unified Huntingtons Disease Rating Scale UHDRS score between baseline and study completion
Results Five subjects were recruited for study participation one female and four males Music therapy was found to be a tolerable and feasible treatment for patients with HD 100 adherence and 98 attendance Exit surveys demonstrated strongly positive feelings towards the music therapy treatment program in four of the five subjects one survey was completed with contradictory answers by the subject While there was improvement in UHDRS scores for finger tapping pronationsupination and the Luria these changes did not achieve statistical significance with the small sample size in this study
Conclusions Music therapy was well tolerated among subjects with HD in this small study Future studies are now being planned to look at the efficacy of this intervention in a larger population of HD subjects
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None