Ignite Creation Date:
2024-05-06 @ 3:23 AM
Last Modification Date:
2024-10-26 @ 11:32 AM
Study NCT ID:
NCT02270996
Status:
WITHDRAWN
Last Update Posted:
2018-03-20
First Post:
2014-10-08
Brief Title:
Antimicrobial Stewardship in Pediatric Surgery
Sponsor:
Alberta Childrens Hospital
Organization:
Alberta Childrens Hospital
Study Overview
Official Title:
An Antimicrobial Stewardship Intervention Program in Pediatric Surgery
Status:
WITHDRAWN
Status Verified Date:
2018-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
AbxPS
Brief Summary:
Acute appendicitis is a common surgical emergency in children Non-perforated appendicitis patients do not require antibiotics after appendectomy Although guidelines and recommendations exist to decrease post-operative antibiotic mis-use after appendectomy surgeons continue to prescribe unwarranted antibiotics
The aim of this study is to determine if an Antimicrobial Stewardship Program in Pediatric Surgery will decrease the use of un-warranted antibiotics
The aim of this study is to determine if an Antimicrobial Stewardship Program in Pediatric Surgery will decrease the use of un-warranted antibiotics
Detailed Description:
Many surgeons continue to treat non-perforated or borderline perforated appendicitis with postoperative antibiotics despite an evidence-based definition of perforation in the pediatric surgical literature and many guidelines and recommendations that specify that no postoperative antibiotics are required Children with perforated appendicitis are also often treated with longer-than-necessary courses of antibiotics Although surgeons may feel that they only prescribe additional doses on occasion evidence suggests that this behavior occurs in over 50 of children with non-perforated appendicitis
These additional doses contribute to a longer length of stay excess costs to the health care system and disrupt patient flow Additionally the patients are exposed to more antibiotics and their potential for adverse effects such as incorrect dose incorrect medication allergic reaction antimicrobial resistance or c difficile infection
Antimicrobial stewardship programs have been successful in pediatrics and adult general surgery in curbing unwarranted antibiotic use but have never been evaluated in pediatric general surgery
These additional doses contribute to a longer length of stay excess costs to the health care system and disrupt patient flow Additionally the patients are exposed to more antibiotics and their potential for adverse effects such as incorrect dose incorrect medication allergic reaction antimicrobial resistance or c difficile infection
Antimicrobial stewardship programs have been successful in pediatrics and adult general surgery in curbing unwarranted antibiotic use but have never been evaluated in pediatric general surgery
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None