Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00172263
Status:
WITHDRAWN
Last Update Posted:
2012-12-10
First Post:
2005-09-12
Brief Title:
The Interaction Between Severe Acute Respiratory Distress Syndrome Viral Proteins and Monocytes
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
None
Status:
WITHDRAWN
Status Verified Date:
2012-12
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Severe acute respiratory syndrome SARS is a new threat to public health since November 2002 The SARS is highly contagious and is believed to be transmitted by person-to-person through droplet and direct contact The patients present with fever chills cough myalgia dyspnea and diarrhea The symptoms aggravate in the second week and nearly 40 of the patients develop respiratory failure that requires assisted ventilation The mortality rate is reported as 65-7
After several months the world scientists found the etiology to be a new coronavirus not belonging to the previous coronavirus group I II and III The new virus is called SARS associated coronavirus SARS-CoV
Although the high morbidity and mortality of SARS occurred in adults there was rare mortality reported in the children The report from Hong Kong pointed out that the symptoms of SARS in younger children were milder and the clinical course was not as aggressive as in adults Therefore the aim of the project is to design the experiment to see the differences of immunological responses to SARS-CoV protein in healthy younger children teenagers and adults The investigators hope that the result could explain the reason for milder disease in younger children and the immunological pathogenesis of SARS
After several months the world scientists found the etiology to be a new coronavirus not belonging to the previous coronavirus group I II and III The new virus is called SARS associated coronavirus SARS-CoV
Although the high morbidity and mortality of SARS occurred in adults there was rare mortality reported in the children The report from Hong Kong pointed out that the symptoms of SARS in younger children were milder and the clinical course was not as aggressive as in adults Therefore the aim of the project is to design the experiment to see the differences of immunological responses to SARS-CoV protein in healthy younger children teenagers and adults The investigators hope that the result could explain the reason for milder disease in younger children and the immunological pathogenesis of SARS
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None