Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00172536
Status:
COMPLETED
Last Update Posted:
2011-04-22
First Post:
2005-09-12
Brief Title:
Effects of Exercise Training on Left Ventricular Function in Type 2 Diabetic Patients Post Coronary Artery Bypass Graft
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
Effects of Exercise Training on Left Ventricular Function in Type 2 Diabetic Patients Post Coronary Artery Bypass Graft
Status:
COMPLETED
Status Verified Date:
2011-03
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to investigate the changes of cardiorespiratory fitness and left ventricular function in type 2 diabetes after uncomplicated coronary artery bypass graft CABG surgery
We hypothesize that exercise capacity left ventricular diastolic function and biochemical data improves after 12-wk exercise training in patients with type 2 diabetes underwent CABG
We hypothesize that exercise capacity left ventricular diastolic function and biochemical data improves after 12-wk exercise training in patients with type 2 diabetes underwent CABG
Detailed Description:
Patients with type 2 diabetes mellitus have higher incidence of coronary artery disease or left ventricular dysfunction particularly diastolic dysfunction Coronary artery bypass surgery is known to decrease the mortality rate in diabetes Further exercise training can improve their cardiorespiratory fitness and the control of risk factors in these patients However the extent of improvement and the mechanism especially the changes in left ventricular function in diabetes after exercise training have not been fully explored
Subjects will be assigned to the intervention or control group by randomization Subjects in the intervention group will receive 60 VO2 max moderate aerobic exercise training twice per week under supervision and three times per week at home for 12 weeks All subjects receive left ventricular function test by echocardiography and impedance cardiography graded maximal exercise test and biochemical analyses of sugar and lipid before and after 12 weeks Their dietary intake and physical activity will be inquired every 4 weeks by questionnaires
Subjects will be assigned to the intervention or control group by randomization Subjects in the intervention group will receive 60 VO2 max moderate aerobic exercise training twice per week under supervision and three times per week at home for 12 weeks All subjects receive left ventricular function test by echocardiography and impedance cardiography graded maximal exercise test and biochemical analyses of sugar and lipid before and after 12 weeks Their dietary intake and physical activity will be inquired every 4 weeks by questionnaires
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None