Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00172276
Status:
COMPLETED
Last Update Posted:
2005-09-15
First Post:
2005-09-12
Brief Title:
Angiotensin Converting Enzyme Gene Polymorphism in Children With Idiopathic Nephrotic Syndrome
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2005-06
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Aims This study was conducted to examine the association between the ACE insertiondeletion ID genotype distribution in children with idiopathic nephrotic syndrome and the response to steroid therapy
Patients and Methods The patients with idiopathic nephrotic syndrome were divided into 2 groups according to their clinical response to steroid SS group including infrequent and frequent relapsers and non-SS group including steroid resistant SR and steroid dependent SD patients Children without previous renal diseases and negative proteinuria were enrolled as control group in genetic study The genotypes for ACE gene ID polymorphism including DD ID and II were analyzed by the newly developed automatic denaturing high performance liquid chromatography system DHPLC
Patients and Methods The patients with idiopathic nephrotic syndrome were divided into 2 groups according to their clinical response to steroid SS group including infrequent and frequent relapsers and non-SS group including steroid resistant SR and steroid dependent SD patients Children without previous renal diseases and negative proteinuria were enrolled as control group in genetic study The genotypes for ACE gene ID polymorphism including DD ID and II were analyzed by the newly developed automatic denaturing high performance liquid chromatography system DHPLC
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None