Ignite Creation Date:
2024-05-05 @ 11:55 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00179010
Status:
TERMINATED
Last Update Posted:
2019-05-07
First Post:
2005-09-13
Brief Title:
AMP as a Better Delivery System of Adenosine
Sponsor:
Vanderbilt University Medical Center
Organization:
Vanderbilt University Medical Center
Study Overview
Official Title:
Use of AMP to Improve Tissue Delivery of Adenosine
Status:
TERMINATED
Status Verified Date:
2019-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Study was terminated because funding could not be secured
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Adenosine and AMP are substances normally present in the body Adenosine is also given for the treatment of some heart rhythm problems and may be used to reduce heart damage during heart attacks The problem in using adenosine is that it is taken up by cells and therefore very little of the adenosine we give by vein or in the artery actually reaches the tissue We propose to use AMP as a way to improve delivery of adenosine AMP is inactive by itself but is converted to adenosine in tissue We hope that by giving AMP we will increase levels of adenosine in tissue To see if this is true we will give either adenosine or AMP into the forearm artery while we measure how much adenosine reaches the forearm tissue
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
True
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None