Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:02 AM
Study NCT ID:
NCT00001159
Status:
RECRUITING
Last Update Posted:
2024-07-12
First Post:
1999-11-03
Brief Title:
Natural History of Thyroid Function Disorders
Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases NIDDK
Organization:
National Institutes of Health Clinical Center CC
Study Overview
Official Title:
Natural History of Thyroid Function Disorders
Status:
RECRUITING
Status Verified Date:
2024-04-02
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Participants in this study will be patients diagnosed with or suspected to have a thyroid function disorder These conditions may include hypothyroidism hyperthyroidism thyroid hormone resistance Graves Dermopathy and thyroid-stimulating hormone TSH secreting pituitary adenomas
The main purpose of this study is to further understand the natural history clinical presentation and genetics of thyroid function disorders Many of the tests performed are in the context of standard medical care that is offered to all patients with thyroid function disorders In addition blood and tissue samples may be taken for research and genetic studies
The main purpose of this study is to further understand the natural history clinical presentation and genetics of thyroid function disorders Many of the tests performed are in the context of standard medical care that is offered to all patients with thyroid function disorders In addition blood and tissue samples may be taken for research and genetic studies
Detailed Description:
Patients with thyroid function abnormalities hyperthyroidism hypothyroidism are studied and treated in this protocol Patients undergo routine history and physical examination standard endocrine blood and urine tests a standard TRH test thyroid nuclear medicine scans thyroidal radioiodine RAI or technetium 99mTc uptake measurements as well as X-ray computed tomography CT or magnetic resonance imaging MRI studies or other standard diagnostic procedures as clinically indicated
The goals of this study are
1 To understand the pathophysiology and various causes of thyroid function abnormalities eg hyperthyroidism hypothyroidism
2 To longitudinally follow the effects of standard therapies for patients with abnormal thyroid functions
3 To create a repository of clinical data and biospecimens for future research of thyroid disorders
Our objective will be accomplished by obtaining clinical data and biospecimens during standard care procedures and tests performed on enrolled subjects being evaluated as an outpatient in the clinic or as an inpatient at the NIH Clinical Center
The goals of this study are
1 To understand the pathophysiology and various causes of thyroid function abnormalities eg hyperthyroidism hypothyroidism
2 To longitudinally follow the effects of standard therapies for patients with abnormal thyroid functions
3 To create a repository of clinical data and biospecimens for future research of thyroid disorders
Our objective will be accomplished by obtaining clinical data and biospecimens during standard care procedures and tests performed on enrolled subjects being evaluated as an outpatient in the clinic or as an inpatient at the NIH Clinical Center
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
False
Is a FDA Regulated Device?:
False
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 77-DK-0002 | None | None | None |