Ignite Creation Date:
2024-05-06 @ 3:14 AM
Last Modification Date:
2024-10-26 @ 11:30 AM
Study NCT ID:
NCT02231073
Status:
COMPLETED
Last Update Posted:
2019-07-25
First Post:
2014-08-18
Brief Title:
Exercise Brain Imaging Cognition and Gait in Parkinsonism
Sponsor:
Oregon Health and Science University
Organization:
Oregon Health and Science University
Study Overview
Official Title:
Peripheral and Central Postural Disorders in the Elderly
Status:
COMPLETED
Status Verified Date:
2019-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
EEforPD
Brief Summary:
There is emerging research detailing the relationship between balancegaitfalls and cognition Imaging studies also suggest a link between structural and functional changes in the frontal lobe a region commonly associated with cognitive function and mobility People with Parkinsons disease have important changes in cognitive function that may impact rehabilitation efficacy Our underlying hypothesis is that cognitive function and frontal lobe connections with the basal ganglia and brainstem posturelocomotor centers are responsible for postural deficits in people with Parkinsons disease and play a role in rehabilitation efficacy The purpose of this study is to 1 determine if people with Parkinsons disease can improve mobility andor cognition after partaking in a cognitively challenging mobility exercise program and 2 determine if cognition and brain circuitry deficits predict responsiveness to exercise rehabilitation
Design This study is a randomized cross-over controlled intervention to take place at a University Balance Disorders Laboratory The study participants will be people with Parkinsons disease who meet inclusion criteria for the study The intervention will be 6 weeks of group exercise case and 6 weeks of group education control The exercise is a cognitively challenging program based on the Agility Boot Camp for people with PD The education program is a 6-week program to teach people how to better live with a chronic disease The primary outcome measure is the MiniBESTest and the secondary outcomes are measures of mobility cognition and neural imaging
Discussion The results from this study will further our understanding of the relationship between cognition and mobility with a focus on brain circuitry as it relates to rehabilitation potential
Design This study is a randomized cross-over controlled intervention to take place at a University Balance Disorders Laboratory The study participants will be people with Parkinsons disease who meet inclusion criteria for the study The intervention will be 6 weeks of group exercise case and 6 weeks of group education control The exercise is a cognitively challenging program based on the Agility Boot Camp for people with PD The education program is a 6-week program to teach people how to better live with a chronic disease The primary outcome measure is the MiniBESTest and the secondary outcomes are measures of mobility cognition and neural imaging
Discussion The results from this study will further our understanding of the relationship between cognition and mobility with a focus on brain circuitry as it relates to rehabilitation potential
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 2R01AG006457 | NIH | None | httpsreporternihgovquickSearch2R01AG006457 |