Ignite Creation Date:
2024-05-06 @ 3:14 AM
Last Modification Date:
2024-10-26 @ 11:30 AM
Study NCT ID:
NCT02233686
Status:
COMPLETED
Last Update Posted:
2015-07-15
First Post:
2014-08-29
Brief Title:
A Study to Assess the Efficacy of XEN-D0501 in Reducing the Cough Frequency in Patients With COPD
Sponsor:
Xention Ltd
Organization:
Xention Ltd
Study Overview
Official Title:
A Double-blind Randomised Placebo-controlled Crossover Study to Assess the Efficacy of XEN-D0501 a Transient Receptor Potential Vanilloid Receptor 1 TRPV1 Antagonist in Reducing the Frequency of Cough in Patients With Chronic Obstructive Pulmonary Disease
Status:
COMPLETED
Status Verified Date:
2015-07
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The purpose of this study is to determine the effectiveness of XEN-D0501 over placebo in reducing the daytime cough frequency in patients with chronic obstructive pulmonary disease COPD
The effectiveness of XEN-D0501 placebo in reducing capsaicin cough responses objective 24-hour cough frequency hourly change in cough frequency cough severity via visual analogue scale VAS urge to cough via VAS global rating of change scale Clinical COPD Questionnaire CCQ Leicester Cough Questionnaire LCQ and St Georges Respiratory Questionnaire SGRQ-C will be evaluated
The effectiveness of XEN-D0501 placebo in reducing capsaicin cough responses objective 24-hour cough frequency hourly change in cough frequency cough severity via visual analogue scale VAS urge to cough via VAS global rating of change scale Clinical COPD Questionnaire CCQ Leicester Cough Questionnaire LCQ and St Georges Respiratory Questionnaire SGRQ-C will be evaluated
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None