Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00178919
Status:
COMPLETED
Last Update Posted:
2013-06-04
First Post:
2005-09-12
Brief Title:
Nitric Oxide and the Autonomic Nervous System
Sponsor:
Vanderbilt University
Organization:
Vanderbilt University
Study Overview
Official Title:
Cardiovascular Regulation AutonomicMetabolic Mechanisms PO1 HL56693 Project 4 Cardiovascular Regulation AutonomicMetabolic Mechanisms
Status:
COMPLETED
Status Verified Date:
2013-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The amount of blood flowing to the different parts of the body is regulated by the autonomic automatic nerves and by local factors produced by the blood vessels Nitric oxide NO is one of the most important of these metabolic factors If the production of NO is slowed or stopped the amount of blood to the different parts of the body is decreased There is increasing knowledge that NO mechanisms are impaired in a number of medical conditions NO function is reduced in patients with risk factors for atherosclerosis hardening of the arteries such as hypercholesterolemia patients with high cholesterol or diabetes mellitus and is also impaired in smokers This NO deficiency is believed to contribute to the greater cardiovascular risk that marks these patient populations This study is designed to examine if endothelial nitric oxide is an important control mechanism of blood pressure under normal conditions and if impairment of nitric oxide contributes to hypertension
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| NIH 1RO1HL71172 | None | None | None |