Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:16 AM
Study NCT ID:
NCT00172315
Status:
UNKNOWN
Last Update Posted:
2006-03-29
First Post:
2005-09-12
Brief Title:
Proton Magnetic Resonance Spectroscopy 1H MRS in Evaluating the Bone Marrow Muscle and Adipose Tissue on Normal and Human Immunodeficiency Virus Infected Subjects
Sponsor:
National Taiwan University Hospital
Organization:
National Taiwan University Hospital
Study Overview
Official Title:
Proton Magnetic Resonance Spectroscopy 1H MRS in Evaluating the Bone Marrow Muscle and Adipose Tissue on Normal and Human Immunodeficiency Virus Infected Subjects With Serial Follow-Up
Status:
UNKNOWN
Status Verified Date:
2005-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Magnetic resonance spectroscopy MRS is commonly applied in medicine with 1H proton or 31-phosphorus spectra The proton MRS is often used in evaluating the central nervous system and 31P MRS is used in muscular diseases or neoplasms However the proton MRS is also considered to be applied to the musculoskeletal system because of its profound amount of protons Ballon used the STEAM technique and Schick used the PRESS technique to investigate the lipid and water spectra of the bone marrow and also correlated those with hematological diseases and post-treatment effects Schellinger et al used the STEAM sequence to calculate the lipid content of the vertebral bone marrow and found that it was influenced according to age and sex The investigator had used the proton MRS to evaluate the lipid and water spectra of the femoral head and revealed its significance in predicting avascular necrosis of the femoral head According to the above research literature the investigators considered further investigation of the proton MRS in evaluating the musculoskeletal system
Detailed Description:
Magnetic resonance spectroscopy MRS is commonly applied in medicine with 1H proton or 31-phosphorus spectra The proton MRS is often used in evaluating the central nervous system and 31P MRS is used in muscular diseases or neoplasms However the proton MRS is also considered to be applied to the musculoskeletal system because of its profound amount of protons Ballon used the STEAM technique and Schick used the PRESS technique to investigate the lipid and water spectra of the bone marrow and also correlated those with hematological diseases and post-treatment effects Schellinger et al used the STEAM sequence to calculate the lipid content of the vertebral bone marrow and found that it was influenced according to age and sex The investigator had used the proton MRS to evaluate the lipid and water spectra of the femoral head and revealed its significance in predicting avascular necrosis of the femoral head According to the above research literature the investigators considered further investigation of the proton MRS in evaluating the musculoskeletal system
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None