Ignite Creation Date:
2024-05-06 @ 3:11 AM
Last Modification Date:
2024-10-26 @ 11:29 AM
Study NCT ID:
NCT02228486
Status:
UNKNOWN
Last Update Posted:
2014-08-29
First Post:
2014-08-15
Brief Title:
Relapse Prevention in Alcohol Dependency by Transcranial Direct Current Stimulation Supported Cue Exposure Therapy
Sponsor:
University Hospital Tuebingen
Organization:
University Hospital Tuebingen
Study Overview
Official Title:
Alcohol Cue-Reactivity in Patients With Alcohol Dependency and Effects of Transcranial Direct Current Stimulation tDCS on Cue-exposure Therapy
Status:
UNKNOWN
Status Verified Date:
2014-08
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Relapse is a major risk in substance abuse disorders which is closely related to craving for a substance describing a strong urge for consumption Cue-exposure therapy is an intervention aiming at the reduction of perceived craving by repeated confrontation It is based on the assumption that craving drops after repeated exposure without the reinforcing experience elicited by consumption In the present study patients with alcohol dependency take part in nine cue-exposure training sessions Each session consists of mood induction reflecting a high risk situation with subsequent in vivo confrontation with ones preferred alcoholic beverage followed by the training of coping strategies During the cue-exposure patients focus on perceiving automatic responses to alcohol-related cues We hypothesize that especially patients exhibiting initially high reactions to such cues should profit from this intervention the most The reactions are measured on a subjective craving and physiological level hemodynamics of the prefrontal cortex heart rate variability electrodermal activity Furthermore we want to strengthen the expected training effects during the cue-exposure by an activating transcranial direct current stimulation of the dorsolateral prefrontal cortex which has been shown to be hypoactive in substance abuse disorders We investigate how the cue-exposure training affects the processing of alcoholic cues cue-reactivity and its relation to clinical symptoms of alcohol dependency
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None