Ignite Creation Date:
2024-05-06 @ 3:03 AM
Last Modification Date:
2024-10-26 @ 11:27 AM
Study NCT ID:
NCT02191423
Status:
UNKNOWN
Last Update Posted:
2014-07-16
First Post:
2014-07-09
Brief Title:
Oxytocin and Dyadic Psychotherapy in the Treatment of Post Partum Depression
Sponsor:
Tel-Aviv Sourasky Medical Center
Organization:
Tel-Aviv Sourasky Medical Center
Study Overview
Official Title:
The Effect of Oxytocin on Brain Attachment and Empathy Networks and the Association Between the Brain Response and Treatment Outcome of Brief Dyadic Psychotherapy - in Women Suffering From Postpartum Depression
Status:
UNKNOWN
Status Verified Date:
2014-07
Last Known Status:
NOT_YET_RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Rationale and Hypotheses of the Current Research the investigators speculate that mothers suffering from PPD exhibit high levels of depression and low levels of OXT hence experiencing the interaction with their child as less rewarding which in turn promote further depressive symptoms and interfere with child development While dyadic psychotherapy has been studied in this context it is unknown which depressed women will respond to this type of therapy and whether such a response is mediated by the pro-bonding effect of oxytocin
The aim of this study is three-fold
1 To study the effect of the administration of a single dose 24IU of oxytocin on cerebral circuit processing and connectivity of empathy and attachment
2 To examine whether the clinical response of mothers suffering from postpartum depression to short term dyadic psychotherapy based on improved mother-child interactions can be predicted by a unique brain response pattern to oxytocin
3 To assess the relationship between levels of oxytocin in mother and baby and the effectiveness of psychological dyadic treatment on mothers suffering from postpartum depression
The aim of this study is three-fold
1 To study the effect of the administration of a single dose 24IU of oxytocin on cerebral circuit processing and connectivity of empathy and attachment
2 To examine whether the clinical response of mothers suffering from postpartum depression to short term dyadic psychotherapy based on improved mother-child interactions can be predicted by a unique brain response pattern to oxytocin
3 To assess the relationship between levels of oxytocin in mother and baby and the effectiveness of psychological dyadic treatment on mothers suffering from postpartum depression
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None