Ignite Creation Date:
2024-05-06 @ 3:02 AM
Last Modification Date:
2024-10-26 @ 11:27 AM
Study NCT ID:
NCT02181179
Status:
COMPLETED
Last Update Posted:
2017-10-26
First Post:
2014-07-01
Brief Title:
Examining Yogas Effects on Smoking
Sponsor:
University of Texas at Austin
Organization:
University of Texas at Austin
Study Overview
Official Title:
Examining Yogas Effects on Aspects Related to Stress and Smoking Behavior
Status:
COMPLETED
Status Verified Date:
2017-10
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
The primary aim of this research study is to examine the effects of an 8-week yoga program on aspects related to nicotine dependence stress and coping during a smoking quit attempt
Guided by initial studies reporting on the effects of yoga on putative mediators of smoking relapse ie cortisol distress intolerance withdrawal symptoms the proposed experiment examines the effects of an 8-week yoga practice on nicotine withdrawal intensity by way of aiding withdrawal characteristics predictive of smoking relapse The long-term objectives of the proposed line of research are to 1 inform theoretical models of nicotine withdrawal 2 guide the development of effective alternative interventions for smokers susceptible to relapse during the critical withdrawal period ie smokers low in distress tolerance and 3 to help guide behavioral strategies for treating substance addictions broadly
Guided by initial studies reporting on the effects of yoga on putative mediators of smoking relapse ie cortisol distress intolerance withdrawal symptoms the proposed experiment examines the effects of an 8-week yoga practice on nicotine withdrawal intensity by way of aiding withdrawal characteristics predictive of smoking relapse The long-term objectives of the proposed line of research are to 1 inform theoretical models of nicotine withdrawal 2 guide the development of effective alternative interventions for smokers susceptible to relapse during the critical withdrawal period ie smokers low in distress tolerance and 3 to help guide behavioral strategies for treating substance addictions broadly
Detailed Description:
As the leading cause of preventable death in the US and a major cause for chronic diseasemortality worldwide smoking represents a major public health issue in need of effective interventions to reduce its burden The development of such strategies is best directed by basic research on the biobehavioral processes underlying smoking maintenance and relapse A major predictor of cessation failure is nicotine withdrawal especially among individuals low in distress tolerance DT
Reducing nicotine withdrawal-related distress and relapse in low DT smokers may require the regulation of certain hormones involved in the hypothalamic pituitary axis HPA-axis ie the human stress response Regular practice of yoga a mindfulness-based form of physical activity emerges as a promising strategy for regulating the HPA-axis decreasing withdrawal symptoms and increasing DT thus promoting smoking cessation success
We will randomly assign 50 smokers 10 cigarettes daily low in DT to either an 8-week yoga intervention YOGA or a waitlist control WL prior to undergoing a self-guided quit attempt We hypothesize participants assigned to the yoga condition relative to waitlist will differ on various outcomes assessed throughout the intervention eg quit status negative affective states stress hormonal changes withdrawal and quit day and throughout the 2-week quit follow-up period
More specifically we hypothesize that certain typical maladaptive during-withdrawal changes may be attenuated through YOGA We also hope to obtain initial effect sizes of the advantage of yoga compared to waitlist for point-prevalent abstinence at two weeks following an unaided quit attempt
Reducing nicotine withdrawal-related distress and relapse in low DT smokers may require the regulation of certain hormones involved in the hypothalamic pituitary axis HPA-axis ie the human stress response Regular practice of yoga a mindfulness-based form of physical activity emerges as a promising strategy for regulating the HPA-axis decreasing withdrawal symptoms and increasing DT thus promoting smoking cessation success
We will randomly assign 50 smokers 10 cigarettes daily low in DT to either an 8-week yoga intervention YOGA or a waitlist control WL prior to undergoing a self-guided quit attempt We hypothesize participants assigned to the yoga condition relative to waitlist will differ on various outcomes assessed throughout the intervention eg quit status negative affective states stress hormonal changes withdrawal and quit day and throughout the 2-week quit follow-up period
More specifically we hypothesize that certain typical maladaptive during-withdrawal changes may be attenuated through YOGA We also hope to obtain initial effect sizes of the advantage of yoga compared to waitlist for point-prevalent abstinence at two weeks following an unaided quit attempt
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None