Ignite Creation Date:
2024-05-05 @ 10:17 AM
Last Modification Date:
2024-10-26 @ 9:05 AM
Study NCT ID:
NCT00005458
Status:
COMPLETED
Last Update Posted:
2016-05-13
First Post:
2000-05-25
Brief Title:
Suppressed Anger Blood Pressure and Mortality Follow-up
Sponsor:
National Heart Lung and Blood Institute NHLBI
Organization:
National Heart Lung and Blood Institute NHLBI
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2000-05
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
To re-examine the relationship between suppressed anger elevated blood pressure and all-cause as well as coronary heart disease CHD mortality using data from the Life Change Event Study LCES conducted on a representative sample of the Tecumseh Community Health Study TCHS n696 men and women aged 30-69 in 1971-1972
Detailed Description:
DESIGN NARRATIVE
The psychosocial data eg anger-expression stressful life events and some medical data eg blood pressure smoking were collected in 197172 while additional information about other medical risk factors was collected in 196869 Mortality ascertainment and cause of death was completed by the end of 1989 through TCHS staff using the National Death Index NDI The estimated cumulative 18-year mortality rate as of 1989 for the Tecumseh cohort of the same age as the LCES sample was 26 percent for males and 16 percent for females Approximately 144 deaths were expected Out of the total TCHS cohort deaths 35 percent were estimated to be due to CHD Research questions tested included 1 did suppressed anger predict coronary heart disease mortality as well as all-cause mortality 2 was the relationship between suppressed anger and mortality modified by other risk factors eg blood pressure marital stress gender 3 were there certain anger-coping strategies among married couples which increased mortality risk for one or both members of the marital pair
Analyses were done at three levels for the whole sample separately for males and females and for a subgroup of 192 married couples it was done by pairs To determine univariate association between anger-coping types and all-cause mortality the percent deceased was compared among persons grouped according to their anger responses For the situation-specific and total suppressed anger indices the distribution of scores was divided into thirds The significance of each association was tested using chi-square statistics Logistic regression was employed to test for the significance of the association between anger-coping measures and mortality controlling for sex age education marital stress relative weight smoking systolic blood pressure CHD status bronchitis and FEV1 scores Logistic regression was also used to determine whether any of the risk factors particularly blood pressure gender and marital stress significantly modified the relationship between suppressed anger and mortality The design and measures of this study had the potential to further identify specific person-situation characteristics associated with higher risks of total as well as cause specific mortality which then could be used to make more knowledgeable recommendations for health behavior interventions
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
The psychosocial data eg anger-expression stressful life events and some medical data eg blood pressure smoking were collected in 197172 while additional information about other medical risk factors was collected in 196869 Mortality ascertainment and cause of death was completed by the end of 1989 through TCHS staff using the National Death Index NDI The estimated cumulative 18-year mortality rate as of 1989 for the Tecumseh cohort of the same age as the LCES sample was 26 percent for males and 16 percent for females Approximately 144 deaths were expected Out of the total TCHS cohort deaths 35 percent were estimated to be due to CHD Research questions tested included 1 did suppressed anger predict coronary heart disease mortality as well as all-cause mortality 2 was the relationship between suppressed anger and mortality modified by other risk factors eg blood pressure marital stress gender 3 were there certain anger-coping strategies among married couples which increased mortality risk for one or both members of the marital pair
Analyses were done at three levels for the whole sample separately for males and females and for a subgroup of 192 married couples it was done by pairs To determine univariate association between anger-coping types and all-cause mortality the percent deceased was compared among persons grouped according to their anger responses For the situation-specific and total suppressed anger indices the distribution of scores was divided into thirds The significance of each association was tested using chi-square statistics Logistic regression was employed to test for the significance of the association between anger-coping measures and mortality controlling for sex age education marital stress relative weight smoking systolic blood pressure CHD status bronchitis and FEV1 scores Logistic regression was also used to determine whether any of the risk factors particularly blood pressure gender and marital stress significantly modified the relationship between suppressed anger and mortality The design and measures of this study had the potential to further identify specific person-situation characteristics associated with higher risks of total as well as cause specific mortality which then could be used to make more knowledgeable recommendations for health behavior interventions
The study completion date listed in this record was obtained from the End Date entered in the Protocol Registration and Results System PRS record
Study Oversight
Has Oversight DMC:
Is a FDA Regulated Drug?:
Is a FDA Regulated Device?:
Is an Unapproved Device?:
Is a PPSD?:
Is a US Export?:
Is an FDA AA801 Violation?:
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| R01HL041796 | NIH | None | httpsreporternihgovquickSearchR01HL041796 |