Ignite Creation Date:
2024-05-06 @ 3:00 AM
Last Modification Date:
2024-10-26 @ 11:26 AM
Study NCT ID:
NCT02180009
Status:
COMPLETED
Last Update Posted:
2016-01-28
First Post:
2014-07-01
Brief Title:
Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis
Sponsor:
Chinese PLA General Hospital
Organization:
Chinese PLA General Hospital
Study Overview
Official Title:
Dynamic Changes of Tim-3 on Monocytes and Soluble Tim-3 in Patients With Sepsis
Status:
COMPLETED
Status Verified Date:
2016-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
In this study the investigators will dynamically detect the expression of an immune regulator- T cell Ig and mucin domain protein 3 Tim-3 in patient with sepsis
Detailed Description:
In this study we will collect the peripheral blood of 13571014 day after diagnose of sepsisAll the patients rolled in this study will be divided into three groups which is sepsis severe sepsis and septic shock group according their severity Thenthe flow cytometry will be used to detect the express of Tim-3 on monocyte and ELISA will be used to exam the plasm soluble Tim-3IL-6IL-10IL-12 and TNF-αin the peripheral blood will also be detected We would like to find a new marker to predict the severity and prognosis of sepsis patients
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None