Ignite Creation Date:
2024-05-05 @ 11:54 AM
Last Modification Date:
2024-10-26 @ 9:15 AM
Study NCT ID:
NCT00160927
Status:
UNKNOWN
Last Update Posted:
2007-03-19
First Post:
2005-09-09
Brief Title:
Microvascular Response in Diabetes Mellitus
Sponsor:
University Hospital Angers
Organization:
University Hospital Angers
Study Overview
Official Title:
Microcirculation cutanée et Vasodilatation Induite Par la Pression Non-Nociceptive Chez Les diabètiques
Status:
UNKNOWN
Status Verified Date:
2007-03
Last Known Status:
RECRUITING
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Vascular and neurological mechanisms are both likely to be involved in foot ulcer We recently reported on the hand an original transient pressure-induced vasodilation PIV during a 5 mmHgmin increase of pressure strain using laser Doppler flowmetry This physiological response to non noxious external local pressure strain is a widely protective cutaneous mechanism The impairment of PIV in diabetic subjects may be relevant to the high prevalence of foot ulcer that occurs in these individuals The aim of the project is to analyse the different physiopathological processes involved in PIV impairment in diabetic subjects as compared to matched controls
Detailed Description:
The whole study is a prospective observational study of diabetic type 1 and type 2 subjects focusing on the various physical physiopathological or pharmacological mechanisms that may interfere with the normal response of the cutaneous microcirculationThe study is currently conducted under various parallel groups of patients and control subjects matched on age and sexe Techniques used for the study are only non-invasive investigations such as iontophoresis with laser doppler flowmetry clinical and paraclinical non-invasive investigation of peripheral neuropathy ultrasound imaging of peripheral arteries
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None