Ignite Creation Date:
2024-05-06 @ 2:53 AM
Last Modification Date:
2024-10-26 @ 11:25 AM
Study NCT ID:
NCT02159170
Status:
COMPLETED
Last Update Posted:
2015-01-16
First Post:
2014-06-03
Brief Title:
Cortical Representation of Hyperalgesia Induced by Nerve Growth Factor
Sponsor:
Prof Herta Flor
Organization:
Central Institute of Mental Health Mannheim
Study Overview
Official Title:
Cortical Representation of NGF-induced Hyperalgesia
Status:
COMPLETED
Status Verified Date:
2015-01
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
LOGIN_NGF
Brief Summary:
Intraepidermal injection of nerve growth factor results in a non-inflammatory hyperalgesia for thermal and mechanical stimuli This hyperalgesia is similar to the pathological ailments of patients with neuropathic pain The mechanisms of the cognitive modulation of pain and hyperalgesia are not yet understood in this group of patients The investigators plan to use NGF injection as a model of non-inflammatory neuropathic pain in healthy subjects to investigate the underlying neuronal mechanisms of this hyperalgesia using functional magnetic resonance imaging and resting state network analysis
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None
Secondary IDs
| Secondary ID | Type | Domain | Link |
|---|---|---|---|
| 01ED1010D | OTHER_GRANT | German Ministry for Education and Research | None |