Ignite Creation Date:
2024-05-06 @ 2:52 AM
Last Modification Date:
2024-10-26 @ 11:25 AM
Study NCT ID:
NCT02149914
Status:
UNKNOWN
Last Update Posted:
2014-11-20
First Post:
2014-05-18
Brief Title:
The Changes of Ryodoraku and HRV After PPI Treatment in GERD Patients
Sponsor:
Taichung Tzu Chi Hospital
Organization:
Taichung Tzu Chi Hospital
Study Overview
Official Title:
The Changes of Ryodoraku and HRV After PPI Treatment in GERD Patients
Status:
UNKNOWN
Status Verified Date:
2014-11
Last Known Status:
ENROLLING_BY_INVITATION
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Gastroesophageal reflux diseaseGERD mainly related to the reflux of stomach content induced by the dysfunction of lower esophageal sphincter Proton pump inhibitors PPI can effectively block gastric acid secretion but the drug reactions and the degree of improvement in symptoms are sometimes unpredictable The aim of this study is to investigate the association between the clinical efficacy of PPI in patients with GERD and the personal physical status by Ryodoraku and ANSWatch
Detailed Description:
Gastroesophageal reflux diseaseGERD is a common disease mainly related to the reflux of stomach content induced by the dysfunction of lower esophageal sphincter The common symptoms of GERD are heartburn acid regurgitation chest pain and globus hystericus The methods to treat GERD are changes of lifestyle pharmacotherapy antireflux surgery and endoscopy Proton pump inhibitors PPI can effectively block gastric acid secretion and promote the repair of esophagus but the drug reactions and the degree of improvement in symptoms are sometimes unpredictable Recently there are many instruments used to analyze personal physical status Meridian energy analysis device Ryodoraku is used to assess the energy of meridian system by analysis of resistance of the skin surface as well as the wrist-worn heart rate monitor ANSWatch used to assess the autonomic nervous system by analysis of heart rate variability Therefore the aim of this study is to investigate the association between the clinical efficacy of PPI in patients with GERD and the personal physical status by Ryodoraku and ANSWatch
Investigators will recruit 120 patients with GERD in clinic who have to receive PPIs for four weeks and assess each volunteer before and after taking the medication Assessment methods 1 ANSWatch to assess the autonomic nervous system 2 Ryodoraku to assess the energy of meridian system 3 Upper gastrointestinal endoscopy to assess the grade of reflux esophagitis 4 gastroesophageal reflux disease questionnaire to assess the severity of GERD Investigators analysed and compared the database from the assessments between before and after taking the medication
Investigators anticipate to substantiate that the changes of Ryodoraku and ANSWatch are good predictors for the clinical efficacy of PPI in patients with GERD
Investigators will recruit 120 patients with GERD in clinic who have to receive PPIs for four weeks and assess each volunteer before and after taking the medication Assessment methods 1 ANSWatch to assess the autonomic nervous system 2 Ryodoraku to assess the energy of meridian system 3 Upper gastrointestinal endoscopy to assess the grade of reflux esophagitis 4 gastroesophageal reflux disease questionnaire to assess the severity of GERD Investigators analysed and compared the database from the assessments between before and after taking the medication
Investigators anticipate to substantiate that the changes of Ryodoraku and ANSWatch are good predictors for the clinical efficacy of PPI in patients with GERD
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None