Ignite Creation Date:
2024-05-06 @ 2:49 AM
Last Modification Date:
2024-10-26 @ 11:24 AM
Study NCT ID:
NCT02138149
Status:
COMPLETED
Last Update Posted:
2015-11-17
First Post:
2014-05-12
Brief Title:
Is the Nerve Growth Factor NGF a Useful Biomarker in Neurogenic Bladder Dysfunction After Spinal Cord Injury
Sponsor:
Swiss Paraplegic Research Nottwil
Organization:
Swiss Paraplegic Research Nottwil
Study Overview
Official Title:
None
Status:
COMPLETED
Status Verified Date:
2015-11
Last Known Status:
None
Delayed Posting:
No
If Stopped, Why?:
Not Stopped
Has Expanded Access:
False
If Expanded Access, NCT#:
N/A
Has Expanded Access, NCT# Status:
N/A
Acronym:
None
Brief Summary:
Spinal cord injury SCI almost always affects bladder function as well As a result of this bladder dysfunction individuals with SCI have to undergo regular invasive examination of their bladder function urodynamic examination
The nerve growth factor NGF is released from smooth muscle cells of the bladder and there are reports that the concentration of NGF is elevated in the urine of patients with bladder dysfunction The NGF concentration can also be measured in the blood The concentration of NGF in the blood and urine of SCI individuals has not yet been investigated These concentrations may correlate with the severity of bladder dysfunction and may thus be used to replace or at least reduce the number of the more invasive urodynamic examinations
The hypothesis that urine and blood NGF concentrations in individuals with SCI are higher compared to individuals with healthy bladder function will be tested
The nerve growth factor NGF is released from smooth muscle cells of the bladder and there are reports that the concentration of NGF is elevated in the urine of patients with bladder dysfunction The NGF concentration can also be measured in the blood The concentration of NGF in the blood and urine of SCI individuals has not yet been investigated These concentrations may correlate with the severity of bladder dysfunction and may thus be used to replace or at least reduce the number of the more invasive urodynamic examinations
The hypothesis that urine and blood NGF concentrations in individuals with SCI are higher compared to individuals with healthy bladder function will be tested
Detailed Description:
None
Study Oversight
Has Oversight DMC:
None
Is a FDA Regulated Drug?:
None
Is a FDA Regulated Device?:
None
Is an Unapproved Device?:
None
Is a PPSD?:
None
Is a US Export?:
None
Is an FDA AA801 Violation?:
None